Schultz PG - Search Results

1

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.

Kato N, Sakata T, Breton G, Le Roch KG, Nagle A, Andersen C, Bursulaya B, Henson K, Johnson J, Kumar KA, Marr F, Mason D, McNamara C, Plouffe D, Ramachandran V, Spooner M, Tuntland T, Zhou Y, Peters EC, Chatterjee A, Schultz PG, Ward GE, Gray N, Harper J, Winzeler EA. Kato N, et al. Among authors: schultz pg. Nat Chem Biol. 2008 Jun;4(6):347-56. doi: 10.1038/nchembio.87. Epub 2008 May 4. Nat Chem Biol. 2008. PMID: 18454143

2

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

Gray NS, Wodicka L, Thunnissen AM, Norman TC, Kwon S, Espinoza FH, Morgan DO, Barnes G, LeClerc S, Meijer L, Kim SH, Lockhart DJ, Schultz PG. Gray NS, et al. Among authors: schultz pg. Science. 1998 Jul 24;281(5376):533-8. doi: 10.1126/science.281.5376.533. Science. 1998. PMID: 9677190 Free article.

3

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.

Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Chang YT, et al. Among authors: schultz pg. Chem Biol. 1999 Jun;6(6):361-75. doi: 10.1016/S1074-5521(99)80048-9. Chem Biol. 1999. PMID: 10375538

4

Myoseverin, a microtubule-binding molecule with novel cellular effects.

Rosania GR, Chang YT, Perez O, Sutherlin D, Dong H, Lockhart DJ, Schultz PG. Rosania GR, et al. Among authors: schultz pg. Nat Biotechnol. 2000 Mar;18(3):304-8. doi: 10.1038/73753. Nat Biotechnol. 2000. PMID: 10700146

5

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

Knockaert M, Gray N, Damiens E, Chang YT, Grellier P, Grant K, Fergusson D, Mottram J, Soete M, Dubremetz JF, Le Roch K, Doerig C, Schultz P, Meijer L. Knockaert M, et al. Chem Biol. 2000 Jun;7(6):411-22. doi: 10.1016/s1074-5521(00)00124-1. Chem Biol. 2000. PMID: 10873834

6

Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

Harmse L, van Zyl R, Gray N, Schultz P, Leclerc S, Meijer L, Doerig C, Havlik I. Harmse L, et al. Biochem Pharmacol. 2001 Aug 1;62(3):341-8. doi: 10.1016/s0006-2952(01)00644-x. Biochem Pharmacol. 2001. PMID: 11434907

7

Design of allele-specific protein methyltransferase inhibitors.

Lin Q, Jiang F, Schultz PG, Gray NS. Lin Q, et al. Among authors: schultz pg. J Am Chem Soc. 2001 Nov 28;123(47):11608-13. doi: 10.1021/ja011423j. J Am Chem Soc. 2001. PMID: 11716715

8

Solid-phase synthesis of 2,3,5-trisubstituted indoles.

Wu TY, Ding S, Gray NS, Schultz PG. Wu TY, et al. Among authors: schultz pg. Org Lett. 2001 Nov 29;3(24):3827-30. doi: 10.1021/ol016525t. Org Lett. 2001. PMID: 11720546

9

A concise and traceless linker strategy toward combinatorial libraries of 2,6,9-substituted purines.

Ding S, Gray NS, Ding Q, Schultz PG. Ding S, et al. Among authors: schultz pg. J Org Chem. 2001 Nov 30;66(24):8273-6. doi: 10.1021/jo016010f. J Org Chem. 2001. PMID: 11722241 No abstract available.

10

A combinatorial scaffold approach toward kinase-directed heterocycle libraries.

Ding S, Gray NS, Wu X, Ding Q, Schultz PG. Ding S, et al. Among authors: schultz pg. J Am Chem Soc. 2002 Feb 27;124(8):1594-6. doi: 10.1021/ja0170302. J Am Chem Soc. 2002. PMID: 11853431

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