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Adding new chemistries to the genetic code.
Liu CC, Schultz PG. Liu CC, et al. Annu Rev Biochem. 2010;79:413-44. doi: 10.1146/annurev.biochem.052308.105824. Annu Rev Biochem. 2010. PMID: 20307192 Review.
Site-specific incorporation of novel backbone structures into proteins.
Ellman JA, Mendel D, Schultz PG. Ellman JA, et al. Science. 1992 Jan 10;255(5041):197-200. doi: 10.1126/science.1553546. Science. 1992. PMID: 1553546
An efficient antibody-catalyzed aminoacylation reaction.
Jacobsen JR, Prudent JR, Kochersperger L, Yonkovich S, Schultz PG. Jacobsen JR, et al. Science. 1992 Apr 17;256(5055):365-7. doi: 10.1126/science.256.5055.365. Science. 1992. PMID: 1566082
Probing protein stability with unnatural amino acids.
Mendel D, Ellman JA, Chang Z, Veenstra DL, Kollman PA, Schultz PG. Mendel D, et al. Science. 1992 Jun 26;256(5065):1798-802. doi: 10.1126/science.1615324. Science. 1992. PMID: 1615324
Catalytic antibodies.
Shokat KM, Schultz PG. Shokat KM, et al. Annu Rev Immunol. 1990;8:335-63. doi: 10.1146/annurev.iy.08.040190.002003. Annu Rev Immunol. 1990. PMID: 2188666 Review. No abstract available.
In vitro suppression of an amber mutation by a chemically aminoacylated transfer RNA prepared by runoff transcription.
Noren CJ, Anthony-Cahill SJ, Suich DJ, Noren KA, Griffith MC, Schultz PG. Noren CJ, et al. Nucleic Acids Res. 1990 Jan 11;18(1):83-8. doi: 10.1093/nar/18.1.83. Nucleic Acids Res. 1990. PMID: 2308838 Free PMC article.
Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.
Zuckermann RN, Schultz PG. Zuckermann RN, et al. Proc Natl Acad Sci U S A. 1989 Mar;86(6):1766-70. doi: 10.1073/pnas.86.6.1766. Proc Natl Acad Sci U S A. 1989. PMID: 2467291 Free PMC article.
The use of 5'-phospho-2 deoxyribocytidylylriboadenosine as a facile route to chemical aminoacylation of tRNA.
Robertson SA, Noren CJ, Anthony-Cahill SJ, Griffith MC, Schultz PG. Robertson SA, et al. Nucleic Acids Res. 1989 Dec 11;17(23):9649-60. doi: 10.1093/nar/17.23.9649. Nucleic Acids Res. 1989. PMID: 2602139 Free PMC article.
Generation of a catalytic sequence-specific hybrid DNase.
Corey DR, Pei D, Schultz PG. Corey DR, et al. Biochemistry. 1989 Oct 17;28(21):8277-86. doi: 10.1021/bi00447a004. Biochemistry. 1989. PMID: 2605184
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