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Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid.
Rollema H, Chambers LK, Coe JW, Glowa J, Hurst RS, Lebel LA, Lu Y, Mansbach RS, Mather RJ, Rovetti CC, Sands SB, Schaeffer E, Schulz DW, Tingley FD 3rd, Williams KE. Rollema H, et al. Among authors: schulz dw. Neuropharmacology. 2007 Mar;52(3):985-94. doi: 10.1016/j.neuropharm.2006.10.016. Epub 2006 Dec 8. Neuropharmacology. 2007. PMID: 17157884
Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation.
Coe JW, Brooks PR, Vetelino MG, Wirtz MC, Arnold EP, Huang J, Sands SB, Davis TI, Lebel LA, Fox CB, Shrikhande A, Heym JH, Schaeffer E, Rollema H, Lu Y, Mansbach RS, Chambers LK, Rovetti CC, Schulz DW, Tingley FD 3rd, O'Neill BT. Coe JW, et al. Among authors: schulz dw. J Med Chem. 2005 May 19;48(10):3474-7. doi: 10.1021/jm050069n. J Med Chem. 2005. PMID: 15887955
3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation.
Coe JW, Brooks PR, Wirtz MC, Bashore CG, Bianco KE, Vetelino MG, Arnold EP, Lebel LA, Fox CB, Tingley FD 3rd, Schulz DW, Davis TI, Sands SB, Mansbach RS, Rollema H, O'Neill BT. Coe JW, et al. Among authors: schulz dw. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4889-97. doi: 10.1016/j.bmcl.2005.08.035. Bioorg Med Chem Lett. 2005. PMID: 16171993
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole.
Macor JE, Burkhart CA, Heym JH, Ives JL, Lebel LA, Newman ME, Nielsen JA, Ryan K, Schulz DW, Torgersen LK, et al. Macor JE, et al. Among authors: schulz dw. J Med Chem. 1990 Aug;33(8):2087-93. doi: 10.1021/jm00170a007. J Med Chem. 1990. PMID: 2374139
Synthesis and serotonergic pharmacology of the enantiomers of 3-[(N-methylpyrrolidin-2-yl)methyl]-5-methoxy-1H-indole: discovery of stereogenic differentiation in the aminoethyl side chain of the neurotransmitter serotonin.
Macor JE, Blake J, Fox CB, Johnson C, Koe BK, Lebel LA, Morrone JM, Ryan K, Schmidt AW, Schulz DW, et al. Macor JE, et al. Among authors: schulz dw. J Med Chem. 1992 Nov 13;35(23):4503-5. doi: 10.1021/jm00101a032. J Med Chem. 1992. PMID: 1447752 No abstract available.
56 results