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Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.
Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Drosatos K, et al. Among authors: schulze pc. J Biol Chem. 2011 Oct 21;286(42):36331-9. doi: 10.1074/jbc.M111.272146. Epub 2011 Aug 26. J Biol Chem. 2011. PMID: 21873422 Free PMC article.
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Chokshi A, et al. Among authors: schulze pc. Circulation. 2012 Jun 12;125(23):2844-53. doi: 10.1161/CIRCULATIONAHA.111.060889. Epub 2012 May 14. Circulation. 2012. PMID: 22586279 Free PMC article.
Lipid metabolism and toxicity in the heart.
Goldberg IJ, Trent CM, Schulze PC. Goldberg IJ, et al. Among authors: schulze pc. Cell Metab. 2012 Jun 6;15(6):805-12. doi: 10.1016/j.cmet.2012.04.006. Cell Metab. 2012. PMID: 22682221 Free PMC article.
Chronic ethanol consumption increases cardiomyocyte fatty acid uptake and decreases ventricular contractile function in C57BL/6J mice.
Hu C, Ge F, Hyodo E, Arai K, Iwata S, Lobdell H 4th, Walewski JL, Zhou S, Clugston RD, Jiang H, Zizola CP, Bharadwaj KG, Blaner WS, Homma S, Schulze PC, Goldberg IJ, Berk PD. Hu C, et al. Among authors: schulze pc. J Mol Cell Cardiol. 2013 Jun;59:30-40. doi: 10.1016/j.yjmcc.2013.02.005. Epub 2013 Feb 16. J Mol Cell Cardiol. 2013. PMID: 23422163 Free PMC article.
Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function.
Khan RS, Lin Y, Hu Y, Son NH, Bharadwaj KG, Palacios C, Chokshi A, Ji R, Yu S, Homma S, Schulze PC, Tian R, Goldberg IJ. Khan RS, et al. Among authors: schulze pc. Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1339-47. doi: 10.1152/ajpendo.00349.2013. Epub 2013 Oct 1. Am J Physiol Endocrinol Metab. 2013. PMID: 24085031 Free PMC article.
375 results