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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2005 1
2006 1
2007 1
2008 4
2009 4
2010 2
2012 2
2013 4
2014 7
2015 6
2016 11
2017 10
2018 7
2019 9
2020 5
2021 6
2022 6
2023 10
2024 3

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92 results

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Page 1
Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage.
Arvanitaki ES, Goulielmaki E, Gkirtzimanaki K, Niotis G, Tsakani E, Nenedaki E, Rouska I, Kefalogianni M, Xydias D, Kalafatakis I, Psilodimitrakopoulos S, Karagogeos D, Schumacher B, Stratakis E, Garinis GA. Arvanitaki ES, et al. Among authors: schumacher b. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2317402121. doi: 10.1073/pnas.2317402121. Epub 2024 Apr 18. Proc Natl Acad Sci U S A. 2024. PMID: 38635632
DNA repair deficiencies and neurodegeneration.
Ropert B, Gallrein C, Schumacher B. Ropert B, et al. Among authors: schumacher b. DNA Repair (Amst). 2024 Apr 16;138:103679. doi: 10.1016/j.dnarep.2024.103679. Online ahead of print. DNA Repair (Amst). 2024. PMID: 38640601
Genome Instability and DNA Repair in Somatic and Reproductive Aging.
Panier S, Wang S, Schumacher B. Panier S, et al. Among authors: schumacher b. Annu Rev Pathol. 2024 Jan 24;19:261-290. doi: 10.1146/annurev-pathmechdis-051122-093128. Epub 2023 Oct 13. Annu Rev Pathol. 2024. PMID: 37832947 Free article. Review.
The novel role of lymphatic vessels in the pathogenesis of ocular diseases.
Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y, Fassbender S, Jantsch J, Zhang W, Enders P, Bachmann B, Bock F, Cursiefen C. Clahsen T, et al. Among authors: schumacher b. Prog Retin Eye Res. 2023 Sep;96:101157. doi: 10.1016/j.preteyeres.2022.101157. Epub 2023 Feb 8. Prog Retin Eye Res. 2023. PMID: 36759312 Review.
Mitigating age-related somatic mutation burden.
Vijg J, Schumacher B, Abakir A, Antonov M, Bradley C, Cagan A, Church G, Gladyshev VN, Gorbunova V, Maslov AY, Reik W, Sharifi S, Suh Y, Walsh K. Vijg J, et al. Among authors: schumacher b. Trends Mol Med. 2023 Jul;29(7):530-540. doi: 10.1016/j.molmed.2023.04.002. Epub 2023 Apr 29. Trends Mol Med. 2023. PMID: 37121869 Free article. Review.
Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling.
Selle J, Bohl K, Höpker K, Wilke R, Dinger K, Kasper P, Abend B, Schermer B, Müller RU, Kurschat C, Nüsken KD, Nüsken E, Meyer D, Savai Pullamsetti S, Schumacher B, Dötsch J, Alcazar MAA. Selle J, et al. Among authors: schumacher b. Int J Mol Sci. 2023 Jan 28;24(3):2508. doi: 10.3390/ijms24032508. Int J Mol Sci. 2023. PMID: 36768831 Free PMC article.
Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice.
Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A, Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA. Kasper P, et al. Among authors: schumacher b. Int J Mol Sci. 2022 May 17;23(10):5609. doi: 10.3390/ijms23105609. Int J Mol Sci. 2022. PMID: 35628414 Free PMC article.
UV Protection in the Cornea: Failure and Rescue.
Volatier T, Schumacher B, Cursiefen C, Notara M. Volatier T, et al. Among authors: schumacher b. Biology (Basel). 2022 Feb 10;11(2):278. doi: 10.3390/biology11020278. Biology (Basel). 2022. PMID: 35205145 Free PMC article. Review.
Molecular pathology of rare progeroid diseases.
Rieckher M, Garinis GA, Schumacher B. Rieckher M, et al. Among authors: schumacher b. Trends Mol Med. 2021 Sep;27(9):907-922. doi: 10.1016/j.molmed.2021.06.011. Epub 2021 Jul 13. Trends Mol Med. 2021. PMID: 34272172 Review.
The central role of DNA damage in the ageing process.
Schumacher B, Pothof J, Vijg J, Hoeijmakers JHJ. Schumacher B, et al. Nature. 2021 Apr;592(7856):695-703. doi: 10.1038/s41586-021-03307-7. Epub 2021 Apr 28. Nature. 2021. PMID: 33911272 Free PMC article. Review.
Principles of the Molecular and Cellular Mechanisms of Aging.
da Silva PFL, Schumacher B. da Silva PFL, et al. Among authors: schumacher b. J Invest Dermatol. 2021 Apr;141(4S):951-960. doi: 10.1016/j.jid.2020.11.018. Epub 2021 Jan 29. J Invest Dermatol. 2021. PMID: 33518357 Free article. Review.
ARDD 2020: from aging mechanisms to interventions.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. Mkrtchyan GV, et al. Among authors: schumacher b. Aging (Albany NY). 2020 Dec 30;12(24):24484-24503. doi: 10.18632/aging.202454. Epub 2020 Dec 30. Aging (Albany NY). 2020. PMID: 33378272 Free PMC article. Review.
DNA Damaged Induced Cell Death in Oocytes.
Gebel J, Tuppi M, Sänger N, Schumacher B, Dötsch V. Gebel J, et al. Among authors: schumacher b. Molecules. 2020 Dec 3;25(23):5714. doi: 10.3390/molecules25235714. Molecules. 2020. PMID: 33287328 Free PMC article. Review.
A C. elegans model for neurodegeneration in Cockayne syndrome.
Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M, Schumacher B. Lopes AFC, et al. Among authors: schumacher b. Nucleic Acids Res. 2020 Nov 4;48(19):10973-10985. doi: 10.1093/nar/gkaa795. Nucleic Acids Res. 2020. PMID: 33021672 Free PMC article.
DNA damage responses in ageing.
da Silva PFL, Schumacher B. da Silva PFL, et al. Among authors: schumacher b. Open Biol. 2019 Nov 29;9(11):190168. doi: 10.1098/rsob.190168. Epub 2019 Nov 20. Open Biol. 2019. PMID: 31744423 Free PMC article. Review.
Age is in the nucleus.
Schumacher B, Vijg J. Schumacher B, et al. Nat Metab. 2019 Oct;1(10):931-932. doi: 10.1038/s42255-019-0125-9. Nat Metab. 2019. PMID: 32694837 Free PMC article.
UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors.
Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y. Jachimowicz RD, et al. Among authors: schumacher b. Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3. Cell. 2019. PMID: 30612738 Free article.
The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression.
Torgovnick A, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F, Vogel W, Klümper N, Nolte H, Wittersheim M, Tharun L, Castiglione R, Krüger M, Schauss A, Perner S, Pasparakis M, Büttner R, Persigehl T, Hucho T, Herter-Sprie GS, Schumacher B, Reinhardt HC. Torgovnick A, et al. Among authors: schumacher b. Cell Rep. 2018 Oct 23;25(4):1027-1039.e6. doi: 10.1016/j.celrep.2018.09.079. Cell Rep. 2018. PMID: 30355482 Free article.
DNA damage responses and p53 in the aging process.
Ou HL, Schumacher B. Ou HL, et al. Among authors: schumacher b. Blood. 2018 Feb 1;131(5):488-495. doi: 10.1182/blood-2017-07-746396. Epub 2017 Nov 15. Blood. 2018. PMID: 29141944 Free PMC article. Review.
Nucleotide excision repair as a targetable vulnerability in leukemia.
Lohmann G, Schumacher B, Herling M. Lohmann G, et al. Among authors: schumacher b. Oncotarget. 2017 Dec 6;8(70):114420-114421. doi: 10.18632/oncotarget.22998. eCollection 2017 Dec 29. Oncotarget. 2017. PMID: 29383087 Free PMC article. No abstract available.
Editorial: DNA damage & immunity.
Garinis GA, Schwer B, Schumacher B. Garinis GA, et al. Among authors: schumacher b. Mech Ageing Dev. 2017 Jul;165(Pt A):1-2. doi: 10.1016/j.mad.2017.04.006. Epub 2017 Apr 23. Mech Ageing Dev. 2017. PMID: 28445698 Free PMC article. No abstract available.
Genome instability: Linking ageing and brain degeneration.
Barzilai A, Schumacher B, Shiloh Y. Barzilai A, et al. Among authors: schumacher b. Mech Ageing Dev. 2017 Jan;161(Pt A):4-18. doi: 10.1016/j.mad.2016.03.011. Epub 2016 Mar 31. Mech Ageing Dev. 2017. PMID: 27041231 Review.
Hormesis running hot and cold.
Bujarrabal A, Schumacher B. Bujarrabal A, et al. Among authors: schumacher b. Cell Cycle. 2016 Dec 16;15(24):3335-3336. doi: 10.1080/15384101.2016.1235859. Epub 2016 Sep 29. Cell Cycle. 2016. PMID: 27687575 Free PMC article. No abstract available.
Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner.
Jokić M, Vlašić I, Rinneburger M, Klümper N, Spiro J, Vogel W, Offermann A, Kümpers C, Fritz C, Schmitt A, Riabinska A, Wittersheim M, Michels S, Ozretić L, Florin A, Welcker D, Akyuz MD, Nowak M, Erkel M, Wolf J, Büttner R, Schumacher B, Thomale J, Persigehl T, Maintz D, Perner S, Reinhardt HC. Jokić M, et al. Among authors: schumacher b. Mol Cancer Res. 2016 Nov;14(11):1110-1123. doi: 10.1158/1541-7786.MCR-16-0094. Epub 2016 Aug 11. Mol Cancer Res. 2016. PMID: 27514406
The tumour suppressor CYLD regulates the p53 DNA damage response.
Fernández-Majada V, Welz PS, Ermolaeva MA, Schell M, Adam A, Dietlein F, Komander D, Büttner R, Thomas RK, Schumacher B, Pasparakis M. Fernández-Majada V, et al. Among authors: schumacher b. Nat Commun. 2016 Aug 26;7:12508. doi: 10.1038/ncomms12508. Nat Commun. 2016. PMID: 27561390 Free PMC article.
Systemic DNA damage responses in aging and diseases.
Ribezzo F, Shiloh Y, Schumacher B. Ribezzo F, et al. Among authors: schumacher b. Semin Cancer Biol. 2016 Jun;37-38:26-35. doi: 10.1016/j.semcancer.2015.12.005. Epub 2016 Jan 7. Semin Cancer Biol. 2016. PMID: 26773346 Free PMC article. Review.
p53 in the DNA-Damage-Repair Process.
Williams AB, Schumacher B. Williams AB, et al. Among authors: schumacher b. Cold Spring Harb Perspect Med. 2016 May 2;6(5):a026070. doi: 10.1101/cshperspect.a026070. Cold Spring Harb Perspect Med. 2016. PMID: 27048304 Free PMC article. Review.
Altered lipid metabolism in the aging kidney identified by three layered omic analysis.
Braun F, Rinschen MM, Bartels V, Frommolt P, Habermann B, Hoeijmakers JH, Schumacher B, Dollé ME, Müller RU, Benzing T, Schermer B, Kurschat CE. Braun F, et al. Among authors: schumacher b. Aging (Albany NY). 2016 Mar;8(3):441-57. doi: 10.18632/aging.100900. Aging (Albany NY). 2016. PMID: 26886165 Free PMC article.
Identification of ageing-associated naturally occurring peptides in human urine.
Nkuipou-Kenfack E, Bhat A, Klein J, Jankowski V, Mullen W, Vlahou A, Dakna M, Koeck T, Schanstra JP, Zürbig P, Rudolph KL, Schumacher B, Pich A, Mischak H. Nkuipou-Kenfack E, et al. Among authors: schumacher b. Oncotarget. 2015 Oct 27;6(33):34106-17. doi: 10.18632/oncotarget.5896. Oncotarget. 2015. PMID: 26431327 Free PMC article.
DNA repair mechanisms in cancer development and therapy.
Torgovnick A, Schumacher B. Torgovnick A, et al. Among authors: schumacher b. Front Genet. 2015 Apr 23;6:157. doi: 10.3389/fgene.2015.00157. eCollection 2015. Front Genet. 2015. PMID: 25954303 Free PMC article.
Longevity through DNA damage tolerance.
Castells-Roca L, Mueller MM, Schumacher B. Castells-Roca L, et al. Among authors: schumacher b. Cell Cycle. 2015;14(4):467-8. doi: 10.1080/15384101.2015.1006543. Cell Cycle. 2015. PMID: 25591056 Free PMC article. No abstract available.
Proteome analysis in the assessment of ageing.
Nkuipou-Kenfack E, Koeck T, Mischak H, Pich A, Schanstra JP, Zürbig P, Schumacher B. Nkuipou-Kenfack E, et al. Among authors: schumacher b. Ageing Res Rev. 2014 Nov;18:74-85. doi: 10.1016/j.arr.2014.09.002. Epub 2014 Sep 22. Ageing Res Rev. 2014. PMID: 25257180 Review.
Insights from the worm: the C. elegans model for innate immunity.
Ermolaeva MA, Schumacher B. Ermolaeva MA, et al. Among authors: schumacher b. Semin Immunol. 2014 Aug;26(4):303-9. doi: 10.1016/j.smim.2014.04.005. Epub 2014 May 21. Semin Immunol. 2014. PMID: 24856329 Free PMC article. Review.
Impact of genomic damage and ageing on stem cell function.
Behrens A, van Deursen JM, Rudolph KL, Schumacher B. Behrens A, et al. Among authors: schumacher b. Nat Cell Biol. 2014 Mar;16(3):201-7. doi: 10.1038/ncb2928. Nat Cell Biol. 2014. PMID: 24576896 Free PMC article. Review.
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.
Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T. Höpker K, et al. Among authors: schumacher b. EMBO J. 2012 Oct 17;31(20):3961-75. doi: 10.1038/emboj.2012.236. Epub 2012 Aug 21. EMBO J. 2012. PMID: 22909821 Free PMC article.
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B. Garinis GA, et al. Among authors: schumacher b. Nat Cell Biol. 2009 May;11(5):604-15. doi: 10.1038/ncb1866. Epub 2009 Apr 12. Nat Cell Biol. 2009. PMID: 19363488 Free PMC article.
Sealing the gap between nuclear DNA damage and longevity.
Schumacher B, Hoeijmakers JH, Garinis GA. Schumacher B, et al. Mol Cell Endocrinol. 2009 Feb 5;299(1):112-7. doi: 10.1016/j.mce.2008.10.031. Epub 2008 Nov 5. Mol Cell Endocrinol. 2009. PMID: 19027821 Review.
Delayed and accelerated aging share common longevity assurance mechanisms.
Schumacher B, van der Pluijm I, Moorhouse MJ, Kosteas T, Robinson AR, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JH, van der Horst GT, Garinis GA. Schumacher B, et al. PLoS Genet. 2008 Aug 15;4(8):e1000161. doi: 10.1371/journal.pgen.1000161. PLoS Genet. 2008. PMID: 18704162 Free PMC article.
Age to survive: DNA damage and aging.
Schumacher B, Garinis GA, Hoeijmakers JH. Schumacher B, et al. Trends Genet. 2008 Feb;24(2):77-85. doi: 10.1016/j.tig.2007.11.004. Epub 2008 Jan 14. Trends Genet. 2008. PMID: 18192065 Review.
Cell cycle: check for asynchrony.
Schumacher B, Alpi A, Garter A. Schumacher B, et al. Curr Biol. 2003 Jul 15;13(14):R560-2. doi: 10.1016/s0960-9822(03)00473-1. Curr Biol. 2003. PMID: 12867049 Free article. Review.