Schumacher FF - Search Results

1

Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.

Schumacher FF, Sanchania VA, Tolner B, Wright ZV, Ryan CP, Smith ME, Ward JM, Caddick S, Kay CW, Aeppli G, Chester KA, Baker JR. Schumacher FF, et al. Sci Rep. 2013;3:1525. doi: 10.1038/srep01525. Sci Rep. 2013. PMID: 23519366 Free PMC article.

2

Protein modification, bioconjugation, and disulfide bridging using bromomaleimides.

Smith ME, Schumacher FF, Ryan CP, Tedaldi LM, Papaioannou D, Waksman G, Caddick S, Baker JR. Smith ME, et al. Among authors: schumacher ff. J Am Chem Soc. 2010 Feb 17;132(6):1960-5. doi: 10.1021/ja908610s. J Am Chem Soc. 2010. PMID: 20092331 Free PMC article.

3

In situ maleimide bridging of disulfides and a new approach to protein PEGylation.

Schumacher FF, Nobles M, Ryan CP, Smith ME, Tinker A, Caddick S, Baker JR. Schumacher FF, et al. Bioconjug Chem. 2011 Feb 16;22(2):132-6. doi: 10.1021/bc1004685. Epub 2011 Jan 27. Bioconjug Chem. 2011. PMID: 21271715 Free PMC article.

4

Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation.

Castañeda L, Maruani A, Schumacher FF, Miranda E, Chudasama V, Chester KA, Baker JR, Smith ME, Caddick S. Castañeda L, et al. Among authors: schumacher ff. Chem Commun (Camb). 2013 Sep 25;49(74):8187-9. doi: 10.1039/c3cc45220d. Chem Commun (Camb). 2013. PMID: 23929130 Free PMC article.

5

Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.

Schumacher FF, Nunes JP, Maruani A, Chudasama V, Smith ME, Chester KA, Baker JR, Caddick S. Schumacher FF, et al. Org Biomol Chem. 2014 Oct 7;12(37):7261-9. doi: 10.1039/c4ob01550a. Org Biomol Chem. 2014. PMID: 25103319 Free PMC article.

6

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis.

Ryan CP, Smith ME, Schumacher FF, Grohmann D, Papaioannou D, Waksman G, Werner F, Baker JR, Caddick S. Ryan CP, et al. Among authors: schumacher ff. Chem Commun (Camb). 2011 May 21;47(19):5452-4. doi: 10.1039/c1cc11114k. Epub 2011 Apr 5. Chem Commun (Camb). 2011. PMID: 21465057 Free PMC article.

7

Bromopyridazinedione-mediated protein and peptide bioconjugation.

Chudasama V, Smith ME, Schumacher FF, Papaioannou D, Waksman G, Baker JR, Caddick S. Chudasama V, et al. Among authors: schumacher ff. Chem Commun (Camb). 2011 Aug 21;47(31):8781-3. doi: 10.1039/c1cc12807h. Epub 2011 Jul 7. Chem Commun (Camb). 2011. PMID: 21738916 Free PMC article.

8

Polymeric dibromomaleimides as extremely efficient disulfide bridging bioconjugation and pegylation agents.

Jones MW, Strickland RA, Schumacher FF, Caddick S, Baker JR, Gibson MI, Haddleton DM. Jones MW, et al. Among authors: schumacher ff. J Am Chem Soc. 2012 Jan 25;134(3):1847-52. doi: 10.1021/ja210335f. Epub 2012 Jan 13. J Am Chem Soc. 2012. PMID: 22188166 Free article.

9

Highly efficient disulfide bridging polymers for bioconjugates from radical-compatible dithiophenol maleimides.

Jones MW, Strickland RA, Schumacher FF, Caddick S, Baker JR, Gibson MI, Haddleton DM. Jones MW, et al. Among authors: schumacher ff. Chem Commun (Camb). 2012 Apr 28;48(34):4064-6. doi: 10.1039/c2cc30259d. Epub 2012 Mar 21. Chem Commun (Camb). 2012. PMID: 22436767

10

Zinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration.

Nan R, Farabella I, Schumacher FF, Miller A, Gor J, Martin AC, Jones DT, Lengyel I, Perkins SJ. Nan R, et al. Among authors: schumacher ff. J Mol Biol. 2011 May 13;408(4):714-35. doi: 10.1016/j.jmb.2011.03.006. Epub 2011 Mar 17. J Mol Biol. 2011. PMID: 21396937 Free PMC article.

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