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A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice.
Wang X, Sommerfeld MR, Jahn-Hofmann K, Cai B, Filliol A, Remotti HE, Schwabe RF, Kannt A, Tabas I. Wang X, et al. Among authors: Schwabe RF. Hepatol Commun. 2019 Jul 23;3(9):1221-1234. doi: 10.1002/hep4.1405. eCollection 2019 Sep. Hepatol Commun. 2019. PMID: 31497743 Free PMC article.
Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis.
Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. Kisseleva T, et al. Among authors: Schwabe RF. J Hepatol. 2006 Sep;45(3):429-38. doi: 10.1016/j.jhep.2006.04.014. Epub 2006 Jun 9. J Hepatol. 2006. PMID: 16846660
Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage.
Blaner WS, O'Byrne SM, Wongsiriroj N, Kluwe J, D'Ambrosio DM, Jiang H, Schwabe RF, Hillman EM, Piantedosi R, Libien J. Blaner WS, et al. Among authors: Schwabe RF. Biochim Biophys Acta. 2009 Jun;1791(6):467-73. doi: 10.1016/j.bbalip.2008.11.001. Epub 2008 Nov 24. Biochim Biophys Acta. 2009. PMID: 19071229 Free PMC article. Review.
CCR1 and CCR5 promote hepatic fibrosis in mice.
Seki E, De Minicis S, Gwak GY, Kluwe J, Inokuchi S, Bursill CA, Llovet JM, Brenner DA, Schwabe RF. Seki E, et al. Among authors: Schwabe RF. J Clin Invest. 2009 Jul;119(7):1858-70. doi: 10.1172/jci37444. J Clin Invest. 2009. PMID: 19603542 Free PMC article.
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis.
Kluwe J, Wongsiriroj N, Troeger JS, Gwak GY, Dapito DH, Pradere JP, Jiang H, Siddiqi M, Piantedosi R, O'Byrne SM, Blaner WS, Schwabe RF. Kluwe J, et al. Among authors: Schwabe RF. Gut. 2011 Sep;60(9):1260-8. doi: 10.1136/gut.2010.209551. Epub 2011 Jan 27. Gut. 2011. PMID: 21278145
Deactivation of hepatic stellate cells during liver fibrosis resolution in mice.
Troeger JS, Mederacke I, Gwak GY, Dapito DH, Mu X, Hsu CC, Pradere JP, Friedman RA, Schwabe RF. Troeger JS, et al. Among authors: Schwabe RF. Gastroenterology. 2012 Oct;143(4):1073-83.e22. doi: 10.1053/j.gastro.2012.06.036. Epub 2012 Jun 27. Gastroenterology. 2012. PMID: 22750464 Free PMC article.
The microbiome and cancer.
Schwabe RF, Jobin C. Schwabe RF, et al. Nat Rev Cancer. 2013 Nov;13(11):800-12. doi: 10.1038/nrc3610. Epub 2013 Oct 17. Nat Rev Cancer. 2013. PMID: 24132111 Free PMC article. Review.
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