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Analysis of the distribution of the tick Ixodes ricinus L. (Acari: Ixodidae) in a nature reserve of western Germany using Geographic Information Systems.
Schwarz A, Maier WA, Kistemann T, Kampen H. Schwarz A, et al. Int J Hyg Environ Health. 2009 Jan;212(1):87-96. doi: 10.1016/j.ijheh.2007.12.001. Epub 2008 Feb 11. Int J Hyg Environ Health. 2009. PMID: 18262840
A total of 2832 host-seeking Ixodes ricinus (2660 nymphs and 172 adults) were collected, with maximal abundance in June and a minor second increase in abundance in August. ...Increases in tick abundances in individual habitats were most likely caused by climate chan
A total of 2832 host-seeking Ixodes ricinus (2660 nymphs and 172 adults) were collected, with maximal abundance in June and a
Antibody responses of domestic animals to salivary antigens of Triatomainfestans as biomarkers for low-level infestation of triatomines.
Schwarz A, Sternberg JM, Johnston V, Medrano-Mercado N, Anderson JM, Hume JC, Valenzuela JG, Schaub GA, Billingsley PF. Schwarz A, et al. Int J Parasitol. 2009 Jul 15;39(9):1021-9. doi: 10.1016/j.ijpara.2009.01.010. Epub 2009 Feb 25. Int J Parasitol. 2009. PMID: 19248784 Free PMC article.
Chickens and guinea pigs regularly exposed to this number of triatomines showed a significantly lower anti-saliva antibody titre than animals exposed to 25 adults and fifth instars of four different T.infestans strains originating from Bolivia and from Northern Chile. ...T …
Chickens and guinea pigs regularly exposed to this number of triatomines showed a significantly lower anti-saliva antibody titre than …
Abundance of Ixodes ricinus and prevalence of Borrelia burgdorferi s.l. in the nature reserve Siebengebirge, Germany, in comparison to three former studies from 1978 onwards.
Schwarz A, Hönig V, Vavrušková Z, Grubhoffer L, Balczun C, Albring A, Schaub GA. Schwarz A, et al. Parasit Vectors. 2012 Nov 21;5:268. doi: 10.1186/1756-3305-5-268. Parasit Vectors. 2012. PMID: 23171708 Free PMC article.
METHODS: In 2007 and 2008, host-seeking I. ricinus were collected by monthly blanket dragging at three distinct vegetation sites in the Siebengebirge, a nature reserve and a well visited local recreation area near Bonn, Germany. ...These changes have led to a
METHODS: In 2007 and 2008, host-seeking I. ricinus were collected by monthly blanket dragging at three distinct vegetation sites in the Sieb …
De novo Ixodes ricinus salivary gland transcriptome analysis using two next-generation sequencing methodologies.
Schwarz A, von Reumont BM, Erhart J, Chagas AC, Ribeiro JM, Kotsyfakis M. Schwarz A, et al. FASEB J. 2013 Dec;27(12):4745-56. doi: 10.1096/fj.13-232140. Epub 2013 Aug 20. FASEB J. 2013. PMID: 23964076 Free PMC article.
Our data significantly increase the available genomic information for I. ricinus and form a solid basis for future tick genome/transcriptome assemblies and the functional analysis of effectors that mediate the feeding physiology and parasite-vector interaction of I. ricinu …
Our data significantly increase the available genomic information for I. ricinus and form a solid basis for future tick genome/transc …
A systems level analysis reveals transcriptomic and proteomic complexity in Ixodes ricinus midgut and salivary glands during early attachment and feeding.
Schwarz A, Tenzer S, Hackenberg M, Erhart J, Gerhold-Ay A, Mazur J, Kuharev J, Ribeiro JM, Kotsyfakis M. Schwarz A, et al. Mol Cell Proteomics. 2014 Oct;13(10):2725-35. doi: 10.1074/mcp.M114.039289. Epub 2014 Jul 21. Mol Cell Proteomics. 2014. PMID: 25048707 Free PMC article.
A total of 373 of 1510 identified proteins had higher expression in the salivary glands, but only 110 had correspondingly high transcript levels in the same tissue. ...
A total of 373 of 1510 identified proteins had higher expression in the salivary glands, but only 110 had correspondingly high transc
An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations.
Schwarz A, Medrano-Mercado N, Schaub GA, Struchiner CJ, Bargues MD, Levy MZ, Ribeiro JM. Schwarz A, et al. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3372. doi: 10.1371/journal.pntd.0003372. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25474469 Free PMC article.
As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. ...
As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregat …
Characterization of guinea pig antibody responses to salivary proteins of Triatoma infestans for the development of a triatomine exposure marker.
Dorňáková V, Salazar-Sanchez R, Borrini-Mayori K, Carrion-Navarro O, Levy MZ, Schaub GA, Schwarz A. Dorňáková V, et al. Among authors: schwarz a. PLoS Negl Trop Dis. 2014 Apr 3;8(4):e2783. doi: 10.1371/journal.pntd.0002783. eCollection 2014 Apr. PLoS Negl Trop Dis. 2014. PMID: 24699441 Free PMC article.
These immune responses indicate exposure to triatomines and thus can be a useful epidemiological tool to estimate triatomine infestation. ...Our study resulted in the identification of a potential antigen as useful marker of T. infestans exposure....
These immune responses indicate exposure to triatomines and thus can be a useful epidemiological tool to estimate triatomine infestat …
Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission.
Schwarz A, Juarez JA, Richards J, Rath B, Machaca VQ, Castro YE, Málaga ES, Levy K, Gilman RH, Bern C, Verastegui M, Levy MZ. Schwarz A, et al. Int J Parasitol. 2011 May;41(6):591-4. doi: 10.1016/j.ijpara.2011.02.001. Epub 2011 Mar 21. Int J Parasitol. 2011. PMID: 21426907 Free PMC article.
In a field trial in Quequeña, Peru, sentinel guinea pigs placed in intervention enclosures covered by deltamethrin-treated nets showed significantly lower antibody responses to saliva of Triatoma infestans compared with animals placed in pre-existing control enclosures. .. …
In a field trial in Quequeña, Peru, sentinel guinea pigs placed in intervention enclosures covered by deltamethrin-treated nets showe …
The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin.
Kotál J, Stergiou N, Buša M, Chlastáková A, Beránková Z, Řezáčová P, Langhansová H, Schwarz A, Calvo E, Kopecký J, Mareš M, Schmitt E, Chmelař J, Kotsyfakis M. Kotál J, et al. Among authors: schwarz a. Cell Mol Life Sci. 2019 May;76(10):2003-2013. doi: 10.1007/s00018-019-03034-3. Epub 2019 Feb 12. Cell Mol Life Sci. 2019. PMID: 30747251
Here, we describe and characterize a novel immunomodulatory cystatin, Iristatin, which is upregulated in the salivary glands of feeding Ixodes ricinus ticks. ...
Here, we describe and characterize a novel immunomodulatory cystatin, Iristatin, which is upregulated in the salivary glands of feedi …
In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiology.
Hackenberg M, Langenberger D, Schwarz A, Erhart J, Kotsyfakis M. Hackenberg M, et al. Among authors: schwarz a. RNA. 2017 Aug;23(8):1259-1269. doi: 10.1261/rna.061168.117. Epub 2017 May 4. RNA. 2017. PMID: 28473453 Free PMC article.
For the four most expressed microRNAs from this subset, we analyzed their combinatorial effects upon their host transcriptome using a novel in silico target network approach. ...A control set of highly abundant microRNAs in both saliva and salivary glands indicates …
For the four most expressed microRNAs from this subset, we analyzed their combinatorial effects upon their host transcriptome using a
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