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278 results
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Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
Schwarzer R, Dörken B, Jundt F. Schwarzer R, et al. Leukemia. 2012 Apr;26(4):806-13. doi: 10.1038/leu.2011.265. Epub 2011 Sep 27. Leukemia. 2012. PMID: 21946908
Notch inhibition blocks multiple myeloma cell-induced osteoclast activation.
Schwarzer R, Kaiser M, Acikgoez O, Heider U, Mathas S, Preissner R, Sezer O, Doerken B, Jundt F. Schwarzer R, et al. Leukemia. 2008 Dec;22(12):2273-7. doi: 10.1038/leu.2008.138. Epub 2008 Jun 5. Leukemia. 2008. PMID: 18528422 No abstract available.
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.
Schwarzer R, Nickel N, Godau J, Willie BM, Duda GN, Schwarzer R, Cirovic B, Leutz A, Manz R, Bogen B, Dörken B, Jundt F. Schwarzer R, et al. Blood Cancer J. 2014 Jun 13;4(6):e217. doi: 10.1038/bcj.2014.37. Blood Cancer J. 2014. PMID: 24927406 Free PMC article.
Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.
Jundt F, Acikgöz O, Kwon SH, Schwarzer R, Anagnostopoulos I, Wiesner B, Mathas S, Hummel M, Stein H, Reichardt HM, Dörken B. Jundt F, et al. Among authors: schwarzer r. Leukemia. 2008 Aug;22(8):1587-94. doi: 10.1038/leu.2008.101. Epub 2008 May 1. Leukemia. 2008. PMID: 18449208
Notch and NF-κB signaling pathways in the biology of classical Hodgkin lymphoma.
Schwarzer R, Jundt F. Schwarzer R, et al. Curr Mol Med. 2011 Apr;11(3):236-45. doi: 10.2174/156652411795243423. Curr Mol Med. 2011. PMID: 21375490 Review.
Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.
Kaeda J, Ringel F, Oberender C, Mills K, Quintarelli C, Pane F, Koschmieder S, Slany R, Schwarzer R, Saglio G, Hemmati P, van Lessen A, Amini L, Gresse M, Vagge E, Burmeister T, Serra A, Carson A, Schwarz M, Westermann J, Jundt F, Dörken B, le Coutre P. Kaeda J, et al. Among authors: schwarzer r. Leuk Lymphoma. 2015 Jul;56(7):2105-13. doi: 10.3109/10428194.2014.981175. Epub 2015 Jan 23. Leuk Lymphoma. 2015. PMID: 25363400
Notch signaling in leukemias and lymphomas.
Jundt F, Schwarzer R, Dörken B. Jundt F, et al. Among authors: schwarzer r. Curr Mol Med. 2008 Feb;8(1):51-9. doi: 10.2174/156652408783565540. Curr Mol Med. 2008. PMID: 18289013 Review.
Eukaryotic initiation factor 2alpha phosphorylation is required for B-cell maturation and function in mice.
Mielke N, Schwarzer R, Calkhoven CF, Kaufman RJ, Dörken B, Leutz A, Jundt F. Mielke N, et al. Among authors: schwarzer r. Haematologica. 2011 Sep;96(9):1261-8. doi: 10.3324/haematol.2011.042853. Epub 2011 May 12. Haematologica. 2011. PMID: 21565905 Free PMC article.
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
Schwarzer R, Tondera D, Arnold W, Giese K, Klippel A, Kaufmann J. Schwarzer R, et al. Oncogene. 2005 Feb 10;24(7):1138-49. doi: 10.1038/sj.onc.1208236. Oncogene. 2005. PMID: 15592522
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard PO, Jodal HC, Bommert K, Huard B, Caers J, Carlsen H, Schwarzer R, Schünemann N, Jundt F, Lindeberg MM, Bogen B. Hofgaard PO, et al. Among authors: schwarzer r. PLoS One. 2012;7(12):e51892. doi: 10.1371/journal.pone.0051892. Epub 2012 Dec 20. PLoS One. 2012. PMID: 23284805 Free PMC article.
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