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A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho Londoño J, Reil JC, He T, Oberhofer M, Mannebach S, Mathar I, Philipp SE, Tabellion W, Schweda F, Dietrich A, Kaestner L, Laufs U, Birnbaumer L, Flockerzi V, Freichel M, Lipp P. Camacho Londoño JE, et al. Among authors: schweda f. Eur Heart J. 2015 Sep 1;36(33):2257-66. doi: 10.1093/eurheartj/ehv250. Epub 2015 Jun 11. Eur Heart J. 2015. PMID: 26069213 Free PMC article.
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
Mathar I, Vennekens R, Meissner M, Kees F, Van der Mieren G, Camacho Londoño JE, Uhl S, Voets T, Hummel B, van den Bergh A, Herijgers P, Nilius B, Flockerzi V, Schweda F, Freichel M. Mathar I, et al. Among authors: schweda f. J Clin Invest. 2010 Sep;120(9):3267-79. doi: 10.1172/JCI41348. Epub 2010 Aug 2. J Clin Invest. 2010. PMID: 20679729 Free PMC article.
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. Among authors: schweda f. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Antihypertrophic effects of combined inhibition of the renin-angiotensin system (RAS) and neutral endopeptidase (NEP) in progressive, tachycardia-induced experimental heart failure.
Birner C, Ulucan C, Bratfisch M, Götz T, Dietl A, Schweda F, Riegger GA, Luchner A. Birner C, et al. Among authors: schweda f. Naunyn Schmiedebergs Arch Pharmacol. 2012 Nov;385(11):1117-25. doi: 10.1007/s00210-012-0791-6. Epub 2012 Aug 16. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22895639
108 results