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Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity.
Du Y, Hertoghs N, Duffy FJ, Carnes J, McDermott SM, Neal ML, Schwedhelm KV, McElrath MJ, De Rosa SC, Aitchison JD, Stuart KD. Du Y, et al. Among authors: schwedhelm kv. PLoS Pathog. 2022 Feb 2;18(2):e1010282. doi: 10.1371/journal.ppat.1010282. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35108339 Free PMC article. Clinical Trial.
Achieving intracellular cytokine staining assay concordance on two continents to assess HIV vaccine-induced T-cell responses.
Dintwe OB, De Rosa SC, Huang Y, Flach BS, Manso B, Carter D, Omar FL, Schwedhelm KV, Yu C, Lu H, Morris D, Kee JJ, Voillet V, Stirewalt M, Hural J, Moodie Z, Frahm N, Cohen KW, McElrath MJ, Andersen-Nissen E. Dintwe OB, et al. Among authors: schwedhelm kv. J Leukoc Biol. 2022 Nov;112(5):1167-1181. doi: 10.1002/JLB.5MA0522-668R. Epub 2022 Jul 22. J Leukoc Biol. 2022. PMID: 35866359 Free PMC article.
Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge.
Oyong DA, Duffy FJ, Neal ML, Du Y, Carnes J, Schwedhelm KV, Hertoghs N, Jun SH, Miller H, Aitchison JD, De Rosa SC, Newell EW, McElrath MJ, McDermott SM, Stuart KD. Oyong DA, et al. Among authors: schwedhelm kv. PLoS Pathog. 2023 May 17;19(5):e1011051. doi: 10.1371/journal.ppat.1011051. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37195999 Free PMC article.
Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection.
Duffy FJ, Hertoghs N, Du Y, Neal ML, Oyong D, McDermott S, Minkah N, Carnes J, Schwedhelm KV, McElrath MJ, De Rosa SC, Newell E, Aitchison JD, Stuart K. Duffy FJ, et al. Among authors: schwedhelm kv. Front Immunol. 2022 Dec 15;13:1042741. doi: 10.3389/fimmu.2022.1042741. eCollection 2022. Front Immunol. 2022. PMID: 36591224 Free PMC article.
17 results