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Casein kinase Iepsilon modulates the signaling specificities of dishevelled.
Cong F, Schweizer L, Varmus H. Cong F, et al. Mol Cell Biol. 2004 Mar;24(5):2000-11. doi: 10.1128/mcb.24.5.2000-2011.2004. Mol Cell Biol. 2004. PMID: 14966280 Free PMC article.
Requirement for a nuclear function of beta-catenin in Wnt signaling.
Cong F, Schweizer L, Chamorro M, Varmus H. Cong F, et al. Mol Cell Biol. 2003 Dec;23(23):8462-70. doi: 10.1128/mcb.23.23.8462-8470.2003. Mol Cell Biol. 2003. PMID: 14612392 Free PMC article.
Requirement for Pangolin/dTCF in Drosophila Wingless signaling.
Schweizer L, Nellen D, Basler K. Schweizer L, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5846-51. doi: 10.1073/pnas.1037533100. Epub 2003 May 1. Proc Natl Acad Sci U S A. 2003. PMID: 12730381 Free PMC article.
The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens.
Schweizer L, Rizzo CA, Spires TE, Platero JS, Wu Q, Lin TA, Gottardis MM, Attar RM. Schweizer L, et al. BMC Cell Biol. 2008 Jan 24;9:4. doi: 10.1186/1471-2121-9-4. BMC Cell Biol. 2008. PMID: 18218096 Free PMC article.
Drosophila coracle, a member of the protein 4.1 superfamily, has essential structural functions in the septate junctions and developmental functions in embryonic and adult epithelial cells.
Lamb RS, Ward RE, Schweizer L, Fehon RG. Lamb RS, et al. Mol Biol Cell. 1998 Dec;9(12):3505-19. doi: 10.1091/mbc.9.12.3505. Mol Biol Cell. 1998. PMID: 9843584 Free PMC article.
Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.
Lenhart R, Kirov S, Desilva H, Cao J, Lei M, Johnston K, Peterson R, Schweizer L, Purandare A, Ross-Macdonald P, Fairchild C, Wong T, Wee S. Lenhart R, et al. Mol Cancer Ther. 2015 Oct;14(10):2167-74. doi: 10.1158/1535-7163.MCT-15-0037. Epub 2015 Aug 7. Mol Cancer Ther. 2015. PMID: 26253517
Establishing a high-throughput and automated cancer cell proliferation panel for oncology lead optimization.
Lei M, Ribeiro H, Kolodin G, Gill J, Wang YS, Maloney D, Fan Y, Li S, Myer L, Beluch M, Zhang L, Schweizer L. Lei M, et al. J Biomol Screen. 2013 Oct;18(9):1043-53. doi: 10.1177/1087057113491825. Epub 2013 Jun 3. J Biomol Screen. 2013. PMID: 23733846
Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer.
Attar RM, Jure-Kunkel M, Balog A, Cvijic ME, Dell-John J, Rizzo CA, Schweizer L, Spires TE, Platero JS, Obermeier M, Shan W, Salvati ME, Foster WR, Dinchuk J, Chen SJ, Vite G, Kramer R, Gottardis MM. Attar RM, et al. Cancer Res. 2009 Aug 15;69(16):6522-30. doi: 10.1158/0008-5472.CAN-09-1111. Epub 2009 Aug 4. Cancer Res. 2009. PMID: 19654297
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