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Expression of activation markers in circulating basophils and the relationship to allergen-induced bronchoconstriction in subjects with mild allergic asthma.
Salter BM, Nusca G, Tworek D, Oliveria JP, Smith SG, Watson RM, Scime T, Obminski C, Sehmi R, Gauvreau GM. Salter BM, et al. Among authors: scime t. J Allergy Clin Immunol. 2016 Mar;137(3):936-8.e7. doi: 10.1016/j.jaci.2015.08.024. Epub 2015 Oct 5. J Allergy Clin Immunol. 2016. PMID: 26441227 No abstract available.
Changes in regulatory B-cell levels in bone marrow, blood, and sputum of patients with asthma following inhaled allergen challenge.
Oliveria JP, El-Gammal AI, Yee M, Obminski CD, Scime TX, Watson RM, Howie K, O'Byrne PM, Sehmi R, Gauvreau GM. Oliveria JP, et al. Among authors: scime tx. J Allergy Clin Immunol. 2018 Apr;141(4):1495-1498.e9. doi: 10.1016/j.jaci.2017.11.013. Epub 2017 Dec 6. J Allergy Clin Immunol. 2018. PMID: 29221714 Free article. No abstract available.
The effects of a CCR3 inhibitor, AXP1275, on allergen-induced airway responses in adults with mild-to-moderate atopic asthma.
Gauvreau GM, FitzGerald JM, Boulet LP, Watson RM, Hui L, Villineuve H, Scime TX, Schlatman AR, Obminski C, Kum J, Boehme S, Ly TW, Bacon KB, O'Byrne PM. Gauvreau GM, et al. Among authors: scime tx. Clin Exp Allergy. 2018 Apr;48(4):445-451. doi: 10.1111/cea.13114. Epub 2018 Mar 13. Clin Exp Allergy. 2018. PMID: 29423947 Clinical Trial.
Asthmatic subjects with allergy have elevated levels of IgE+ B cells in the airways.
Oliveria JP, Salter BM, Phan S, Obminski CD, Munoz CE, Smith SG, Scime T, Watson RM, Sehmi R, Gauvreau GM. Oliveria JP, et al. Among authors: scime t. J Allergy Clin Immunol. 2017 Aug;140(2):590-593.e9. doi: 10.1016/j.jaci.2016.12.981. Epub 2017 Feb 16. J Allergy Clin Immunol. 2017. PMID: 28213181 No abstract available.
Comparison of the provocative concentration of methacholine causing a 20% fall in FEV1 between the AeroEclipse II breath-actuated nebulizer and the wright nebulizer in adult subjects with asthma.
El-Gammal AI, Killian KJ, Scime TX, Beaudin S, Schlatman A, Cockcroft DW, Gauvreau GM. El-Gammal AI, et al. Among authors: scime tx. Ann Am Thorac Soc. 2015 Jul;12(7):1039-43. doi: 10.1513/AnnalsATS.201412-571BC. Ann Am Thorac Soc. 2015. PMID: 25871542 Clinical Trial.