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RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.
Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, Di Fiore PP, Oldani A, Garre M, Beznoussenko GV, Palamidessi A, Vecchi M, Chavrier P, Perez F, Scita G. Kajiho H, et al. Among authors: scita g. EMBO Rep. 2016 Jul;17(7):1061-80. doi: 10.15252/embr.201642032. Epub 2016 Jun 2. EMBO Rep. 2016. PMID: 27255086 Free PMC article.
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1.
Wiedmann RM, von Schwarzenberg K, Palamidessi A, Schreiner L, Kubisch R, Liebl J, Schempp C, Trauner D, Vereb G, Zahler S, Wagner E, Müller R, Scita G, Vollmar AM. Wiedmann RM, et al. Among authors: scita g. Cancer Res. 2012 Nov 15;72(22):5976-87. doi: 10.1158/0008-5472.CAN-12-1772. Epub 2012 Sep 17. Cancer Res. 2012. PMID: 22986742
A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.
Frittoli E, Palamidessi A, Marighetti P, Confalonieri S, Bianchi F, Malinverno C, Mazzarol G, Viale G, Martin-Padura I, Garré M, Parazzoli D, Mattei V, Cortellino S, Bertalot G, Di Fiore PP, Scita G. Frittoli E, et al. Among authors: scita g. J Cell Biol. 2014 Jul 21;206(2):307-28. doi: 10.1083/jcb.201403127. J Cell Biol. 2014. PMID: 25049275 Free PMC article.
147 results