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The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration.
Palamidessi A, Frittoli E, Ducano N, Offenhauser N, Sigismund S, Kajiho H, Parazzoli D, Oldani A, Gobbi M, Serini G, Di Fiore PP, Scita G, Lanzetti L. Palamidessi A, et al. Among authors: scita g. Curr Biol. 2013 Dec 2;23(23):2355-64. doi: 10.1016/j.cub.2013.09.060. Epub 2013 Nov 14. Curr Biol. 2013. PMID: 24239119 Free article.
A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.
Frittoli E, Palamidessi A, Marighetti P, Confalonieri S, Bianchi F, Malinverno C, Mazzarol G, Viale G, Martin-Padura I, Garré M, Parazzoli D, Mattei V, Cortellino S, Bertalot G, Di Fiore PP, Scita G. Frittoli E, et al. Among authors: scita g. J Cell Biol. 2014 Jul 21;206(2):307-28. doi: 10.1083/jcb.201403127. J Cell Biol. 2014. PMID: 25049275 Free PMC article.
The CDC42-interacting protein 4 controls epithelial cell cohesion and tumor dissemination.
Rolland Y, Marighetti P, Malinverno C, Confalonieri S, Luise C, Ducano N, Palamidessi A, Bisi S, Kajiho H, Troglio F, Shcherbakova OG, Dunn AR, Oldani A, Lanzetti L, Di Fiore PP, Disanza A, Scita G. Rolland Y, et al. Among authors: scita g. Dev Cell. 2014 Sep 8;30(5):553-68. doi: 10.1016/j.devcel.2014.08.006. Dev Cell. 2014. PMID: 25203208 Free article.
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.
Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, Di Fiore PP, Oldani A, Garre M, Beznoussenko GV, Palamidessi A, Vecchi M, Chavrier P, Perez F, Scita G. Kajiho H, et al. Among authors: scita g. EMBO Rep. 2016 Jul;17(7):1061-80. doi: 10.15252/embr.201642032. Epub 2016 Jun 2. EMBO Rep. 2016. PMID: 27255086 Free PMC article.
Rab2 promotes autophagic and endocytic lysosomal degradation.
Lőrincz P, Tóth S, Benkő P, Lakatos Z, Boda A, Glatz G, Zobel M, Bisi S, Hegedűs K, Takáts S, Scita G, Juhász G. Lőrincz P, et al. Among authors: scita g. J Cell Biol. 2017 Jul 3;216(7):1937-1947. doi: 10.1083/jcb.201611027. Epub 2017 May 8. J Cell Biol. 2017. PMID: 28483915 Free PMC article.
A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior.
Schiano Lomoriello I, Giangreco G, Iavarone C, Tordonato C, Caldieri G, Serio G, Confalonieri S, Freddi S, Bianchi F, Pirroni S, Bertalot G, Viale G, Disalvatore D, Tosoni D, Malabarba MG, Disanza A, Scita G, Pece S, Pilcher BK, Vecchi M, Sigismund S, Di Fiore PP. Schiano Lomoriello I, et al. Among authors: scita g. Nat Commun. 2020 Jun 15;11(1):3020. doi: 10.1038/s41467-020-16836-y. Nat Commun. 2020. PMID: 32541686 Free PMC article.
155 results