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Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk.
Low YL, Taylor JI, Grace PB, Mulligan AA, Welch AA, Scollen S, Dunning AM, Luben RN, Khaw KT, Day NE, Wareham NJ, Bingham SA. Low YL, et al. Nutr Cancer. 2006;56(1):31-9. doi: 10.1207/s15327914nc5601_5. Nutr Cancer. 2006. PMID: 17176215
Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men.
Low YL, Taylor JI, Grace PB, Dowsett M, Folkerd E, Doody D, Dunning AM, Scollen S, Mulligan AA, Welch AA, Luben RN, Khaw KT, Day NE, Wareham NJ, Bingham SA. Low YL, et al. J Nutr. 2005 Nov;135(11):2680-6. doi: 10.1093/jn/135.11.2680. J Nutr. 2005. PMID: 16251630
Modest protective effects of isoflavones from a red clover-derived dietary supplement on cardiovascular disease risk factors in perimenopausal women, and evidence of an interaction with ApoE genotype in 49-65 year-old women.
Atkinson C, Oosthuizen W, Scollen S, Loktionov A, Day NE, Bingham SA. Atkinson C, et al. J Nutr. 2004 Jul;134(7):1759-64. doi: 10.1093/jn/134.7.1759. J Nutr. 2004. PMID: 15226466 Clinical Trial.
Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.
Low YL, Taylor JI, Grace PB, Dowsett M, Scollen S, Dunning AM, Mulligan AA, Welch AA, Luben RN, Khaw KT, Day NE, Wareham NJ, Bingham SA. Low YL, et al. Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):213-20. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15668497
Association of ESR1 gene tagging SNPs with breast cancer risk.
Dunning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodríguez R, Barbosa-Morais NL, Ponder BA; SEARCH, Low YL, Bingham S; EPIC, Haiman CA, Le Marchand L; MEC, Broeks A, Schmidt MK; ABCS, Hopper J, Southey M; ABCFS, Beckmann MW, Fasching PA; BBCC, Peto J, Johnson N; BBCS, Bojesen SE, Nordestgaard B; CGPS, Milne RL, Benitez J; CNIO-BCS, Hamann U, Ko Y; GENICA, Schmutzler RK, Burwinkel B; GC-HBOC, Schürmann P, Dörk T; HABCS, Heikkinen T, Nevanlinna H; HEBCS, Lindblom A, Margolin S; KARBAC, Mannermaa A, Kosma VM; KBCS, Chen X, Spurdle A; kConFab and the AOCS Management Group, Change-Claude J, Flesch-Janys D; MARIE, Couch FJ, Olson JE; for MCBCS, Severi G, Baglietto L; MCCS, Børresen-Dale AL, Kristensen V; NBCS, Hunter DJ, Hankinson SE; NHS, Devilee P, Vreeswijk M; ORIGO, Lissowska J, Brinton L; PBCS, Liu J, Hall P; SASBAC, Kang D, Yoo KY; SEBCS, Shen CY, Yu JC; TWBCS, Anton-Culver H, Ziogoas A; UCIBCS, Sigurdson A, Struewing J; USRTS, Easton DF, Garcia-Closas M, Humphreys MK, Morrison J, Pharoah PD, Pooley KA, Chenevix-Trench G; BCAC. Dunning AM, et al. Hum Mol Genet. 2009 Mar 15;18(6):1131-9. doi: 10.1093/hmg/ddn429. Epub 2009 Jan 6. Hum Mol Genet. 2009. PMID: 19126777 Free PMC article.
TGF-β signaling pathway and breast cancer susceptibility.
Scollen S, Luccarini C, Baynes C, Driver K, Humphreys MK, Garcia-Closas M, Figueroa J, Lissowska J, Pharoah PD, Easton DF, Hesketh R, Metcalfe JC, Dunning AM. Scollen S, et al. Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1112-9. doi: 10.1158/1055-9965.EPI-11-0062. Epub 2011 Apr 28. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21527583 Free PMC article. Clinical Trial.
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.
Baynes C, Healey CS, Pooley KA, Scollen S, Luben RN, Thompson DJ, Pharoah PD, Easton DF, Ponder BA, Dunning AM; SEARCH breast cancer study. Baynes C, et al. Breast Cancer Res. 2007;9(2):R27. doi: 10.1186/bcr1669. Breast Cancer Res. 2007. PMID: 17428325 Free PMC article.
Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes.
Ioannidis JP, Ralston SH, Bennett ST, Brandi ML, Grinberg D, Karassa FB, Langdahl B, van Meurs JB, Mosekilde L, Scollen S, Albagha OM, Bustamante M, Carey AH, Dunning AM, Enjuanes A, van Leeuwen JP, Mavilia C, Masi L, McGuigan FE, Nogues X, Pols HA, Reid DM, Schuit SC, Sherlock RE, Uitterlinden AG; GENOMOS Study. Ioannidis JP, et al. JAMA. 2004 Nov 3;292(17):2105-14. doi: 10.1001/jama.292.17.2105. JAMA. 2004. PMID: 15523071 Clinical Trial.
GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.
Jones AV, Tilley M, Gutteridge A, Hyde C, Nagle M, Ziemek D, Gorman D, Fauman EB, Chen X, Miller MR, Tian C, Hu Y, Hinds DA, Cox P, Scollen S. Jones AV, et al. Among authors: scollen s. Hum Mol Genet. 2017 Apr 1;26(7):1391-1406. doi: 10.1093/hmg/ddx036. Hum Mol Genet. 2017. PMID: 28199695 Free PMC article.
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