Scorah J - Search Results

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Claspin and Chk1 regulate replication fork stability by different mechanisms.

Scorah J, McGowan CH. Scorah J, et al. Cell Cycle. 2009 Apr 1;8(7):1036-43. doi: 10.4161/cc.8.7.8040. Epub 2009 Apr 2. Cell Cycle. 2009. PMID: 19270516 Free PMC article.

A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function.

Scorah J, Dong MQ, Yates JR 3rd, Scott M, Gillespie D, McGowan CH. Scorah J, et al. J Biol Chem. 2008 Jun 20;283(25):17250-9. doi: 10.1074/jbc.M800369200. Epub 2008 Apr 30. J Biol Chem. 2008. PMID: 18448427 Free PMC article.

ATM is required for the cellular response to thymidine induced replication fork stress.

Bolderson E, Scorah J, Helleday T, Smythe C, Meuth M. Bolderson E, et al. Among authors: scorah j. Hum Mol Genet. 2004 Dec 1;13(23):2937-45. doi: 10.1093/hmg/ddh316. Epub 2004 Sep 30. Hum Mol Genet. 2004. PMID: 15459181

Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.

Rodriguez R, Hansen LT, Phear G, Scorah J, Spang-Thomsen M, Cox A, Helleday T, Meuth M. Rodriguez R, et al. Among authors: scorah j. Clin Cancer Res. 2008 Sep 1;14(17):5476-83. doi: 10.1158/1078-0432.CCR-08-0274. Clin Cancer Res. 2008. PMID: 18765539 Free article.

A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.

Wen Q, Scorah J, Phear G, Rodgers G, Rodgers S, Meuth M. Wen Q, et al. Among authors: scorah j. Mol Biol Cell. 2008 Apr;19(4):1693-705. doi: 10.1091/mbc.e07-09-0975. Epub 2008 Feb 6. Mol Biol Cell. 2008. PMID: 18256278 Free PMC article.

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