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Mitochondrial shape changes: orchestrating cell pathophysiology.
Campello S, Scorrano L. Campello S, et al. Among authors: scorrano l. EMBO Rep. 2010 Sep;11(9):678-84. doi: 10.1038/embor.2010.115. Epub 2010 Aug 20. EMBO Rep. 2010. PMID: 20725092 Free PMC article. Review.
Targeting cell death.
Hausenloy DJ, Scorrano L. Hausenloy DJ, et al. Among authors: scorrano l. Clin Pharmacol Ther. 2007 Oct;82(4):370-3. doi: 10.1038/sj.clpt.6100352. Clin Pharmacol Ther. 2007. PMID: 17851576 Review.
The many shapes of mitochondrial death.
Cereghetti GM, Scorrano L. Cereghetti GM, et al. Among authors: scorrano l. Oncogene. 2006 Aug 7;25(34):4717-24. doi: 10.1038/sj.onc.1209605. Oncogene. 2006. PMID: 16892085 Review.
Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21.
Restelli LM, Oettinghaus B, Halliday M, Agca C, Licci M, Sironi L, Savoia C, Hench J, Tolnay M, Neutzner A, Schmidt A, Eckert A, Mallucci G, Scorrano L, Frank S. Restelli LM, et al. Among authors: scorrano l. Cell Rep. 2018 Aug 7;24(6):1407-1414. doi: 10.1016/j.celrep.2018.07.023. Cell Rep. 2018. PMID: 30089252 Free PMC article.
Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease.
Fakruddin M, Wei FY, Suzuki T, Asano K, Kaieda T, Omori A, Izumi R, Fujimura A, Kaitsuka T, Miyata K, Araki K, Oike Y, Scorrano L, Suzuki T, Tomizawa K. Fakruddin M, et al. Among authors: scorrano l. Cell Rep. 2018 Jan 9;22(2):482-496. doi: 10.1016/j.celrep.2017.12.051. Cell Rep. 2018. PMID: 29320742
OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange.
Santo-Domingo J, Giacomello M, Poburko D, Scorrano L, Demaurex N. Santo-Domingo J, et al. Among authors: scorrano l. EMBO J. 2013 Jul 3;32(13):1927-40. doi: 10.1038/emboj.2013.124. Epub 2013 May 28. EMBO J. 2013. PMID: 23714779 Free PMC article.
Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis.
Corrado M, Mariotti FR, Trapani L, Taraborrelli L, Nazio F, Cianfanelli V, Soriano ME, Schrepfer E, Cecconi F, Scorrano L, Campello S. Corrado M, et al. Among authors: scorrano l. EMBO J. 2016 Aug 15;35(16):1793-809. doi: 10.15252/embj.201593727. Epub 2016 Jul 7. EMBO J. 2016. PMID: 27390127 Free PMC article.
Judging a tumor cell by its cover: a matter of mitochondrial contact sites.
Lakshminarayanan S, Scorrano L. Lakshminarayanan S, et al. Among authors: scorrano l. EMBO J. 2017 Jun 1;36(11):1465-1467. doi: 10.15252/embj.201796637. Epub 2017 Mar 16. EMBO J. 2017. PMID: 28302655 Free PMC article.
Molecular definitions of autophagy and related processes.
Galluzzi L, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cecconi F, Choi AM, Chu CT, Codogno P, Colombo MI, Cuervo AM, Debnath J, Deretic V, Dikic I, Eskelinen EL, Fimia GM, Fulda S, Gewirtz DA, Green DR, Hansen M, Harper JW, Jäättelä M, Johansen T, Juhasz G, Kimmelman AC, Kraft C, Ktistakis NT, Kumar S, Levine B, Lopez-Otin C, Madeo F, Martens S, Martinez J, Melendez A, Mizushima N, Münz C, Murphy LO, Penninger JM, Piacentini M, Reggiori F, Rubinsztein DC, Ryan KM, Santambrogio L, Scorrano L, Simon AK, Simon HU, Simonsen A, Tavernarakis N, Tooze SA, Yoshimori T, Yuan J, Yue Z, Zhong Q, Kroemer G. Galluzzi L, et al. Among authors: scorrano l. EMBO J. 2017 Jul 3;36(13):1811-1836. doi: 10.15252/embj.201796697. Epub 2017 Jun 8. EMBO J. 2017. PMID: 28596378 Free PMC article. Review.
The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.
Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F. Loubiere C, et al. Among authors: scorrano l. Sci Rep. 2017 Jul 11;7(1):5040. doi: 10.1038/s41598-017-05052-2. Sci Rep. 2017. PMID: 28698627 Free PMC article.
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