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TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Heinz LX, Lee J, Kapoor U, Kartnig F, Sedlyarov V, Papakostas K, César-Razquin A, Essletzbichler P, Goldmann U, Stefanovic A, Bigenzahn JW, Scorzoni S, Pizzagalli MD, Bensimon A, Müller AC, King FJ, Li J, Girardi E, Mbow ML, Whitehurst CE, Rebsamen M, Superti-Furga G. Heinz LX, et al. Among authors: scorzoni s. Nature. 2020 May;581(7808):316-322. doi: 10.1038/s41586-020-2282-0. Epub 2020 May 13. Nature. 2020. PMID: 32433612 Free PMC article.
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.
Rebsamen M, Pochini L, Stasyk T, de Araújo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G. Rebsamen M, et al. Among authors: scorzoni s. Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7. Nature. 2015. PMID: 25561175 Free PMC article.
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking.
Fauster A, Rebsamen M, Willmann KL, César-Razquin A, Girardi E, Bigenzahn JW, Schischlik F, Scorzoni S, Bruckner M, Konecka J, Hörmann K, Heinz LX, Boztug K, Superti-Furga G. Fauster A, et al. Among authors: scorzoni s. Cell Death Differ. 2019 Jun;26(6):1138-1155. doi: 10.1038/s41418-018-0192-6. Epub 2018 Sep 20. Cell Death Differ. 2019. PMID: 30237509 Free PMC article.
A substrate-based ontology for human solute carriers.
Meixner E, Goldmann U, Sedlyarov V, Scorzoni S, Rebsamen M, Girardi E, Superti-Furga G. Meixner E, et al. Among authors: scorzoni s. Mol Syst Biol. 2020 Jul;16(7):e9652. doi: 10.15252/msb.20209652. Mol Syst Biol. 2020. PMID: 32697042 Free PMC article.
An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client.
Bigenzahn JW, Fauster A, Rebsamen M, Kandasamy RK, Scorzoni S, Vladimer GI, Müller AC, Gstaiger M, Zuber J, Bennett KL, Superti-Furga G. Bigenzahn JW, et al. Among authors: scorzoni s. Mol Cell Proteomics. 2016 Mar;15(3):1139-50. doi: 10.1074/mcp.o115.055350. Mol Cell Proteomics. 2016. PMID: 26933192 Free PMC article.
A time-resolved molecular map of the macrophage response to VSV infection.
Kandasamy RK, Vladimer GI, Snijder B, Müller AC, Rebsamen M, Bigenzahn JW, Moskovskich A, Sabler M, Stefanovic A, Scorzoni S, Brückner M, Penz T, Cleary C, Kralovics R, Colinge J, Bennett KL, Superti-Furga G. Kandasamy RK, et al. Among authors: scorzoni s. NPJ Syst Biol Appl. 2016 Oct 27;2:16027. doi: 10.1038/npjsba.2016.27. eCollection 2016. NPJ Syst Biol Appl. 2016. PMID: 28725479 Free PMC article.
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.
Fauster A, Rebsamen M, Huber KV, Bigenzahn JW, Stukalov A, Lardeau CH, Scorzoni S, Bruckner M, Gridling M, Parapatics K, Colinge J, Bennett KL, Kubicek S, Krautwald S, Linkermann A, Superti-Furga G. Fauster A, et al. Among authors: scorzoni s. Cell Death Dis. 2015 May 21;6(5):e1767. doi: 10.1038/cddis.2015.130. Cell Death Dis. 2015. PMID: 25996294 Free PMC article.
14 results