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Coagulation cascade proteinases in lung injury and fibrosis.

Chambers RC, Scotton CJ. Chambers RC, et al. Among authors: scotton cj. Proc Am Thorac Soc. 2012 Jul;9(3):96-101. doi: 10.1513/pats.201201-006AW. Proc Am Thorac Soc. 2012. PMID: 22802281 Review.

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Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis.

Baliga RS, Scotton CJ, Trinder SL, Chambers RC, MacAllister RJ, Hobbs AJ. Baliga RS, et al. Among authors: scotton cj. Br J Pharmacol. 2014 Jul;171(14):3463-75. doi: 10.1111/bph.12694. Br J Pharmacol. 2014. PMID: 24641440 Free PMC article.

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In search of the fibrotic epithelial cell: opportunities for a collaborative network.

Jenkins G, Blanchard A, Borok Z, Bradding P, Ehrhardt C, Fisher A, Hirani N, Johnson S, Königshoff M, Maher TM, Millar A, Parfrey H, Scotton C, Tetley T, Thickett D, Wolters P; ECIPF workshop. Jenkins G, et al. Thorax. 2012 Feb;67(2):179-82. doi: 10.1136/thoraxjnl-2011-200195. Epub 2011 Jun 15. Thorax. 2012. PMID: 21680569

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Proteinase-activated receptor-1, CCL2, and CCL7 regulate acute neutrophilic lung inflammation.

Mercer PF, Williams AE, Scotton CJ, José RJ, Sulikowski M, Moffatt JD, Murray LA, Chambers RC. Mercer PF, et al. Among authors: scotton cj. Am J Respir Cell Mol Biol. 2014 Jan;50(1):144-57. doi: 10.1165/rcmb.2013-0142OC. Am J Respir Cell Mol Biol. 2014. PMID: 23972264 Free PMC article.

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Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages.

Kallis YN, Scotton CJ, Mackinnon AC, Goldin RD, Wright NA, Iredale JP, Chambers RC, Forbes SJ. Kallis YN, et al. Among authors: scotton cj. PLoS One. 2014 Jan 27;9(1):e86241. doi: 10.1371/journal.pone.0086241. eCollection 2014. PLoS One. 2014. PMID: 24475094 Free PMC article.

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Evidence for a functional thymic stromal lymphopoietin signaling axis in fibrotic lung disease.

Datta A, Alexander R, Sulikowski MG, Nicholson AG, Maher TM, Scotton CJ, Chambers RC. Datta A, et al. Among authors: scotton cj. J Immunol. 2013 Nov 1;191(9):4867-79. doi: 10.4049/jimmunol.1300588. Epub 2013 Sep 30. J Immunol. 2013. PMID: 24081992 Free PMC article.

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Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.

Scotton CJ, Krupiczojc MA, Königshoff M, Mercer PF, Lee YC, Kaminski N, Morser J, Post JM, Maher TM, Nicholson AG, Moffatt JD, Laurent GJ, Derian CK, Eickelberg O, Chambers RC. Scotton CJ, et al. J Clin Invest. 2009 Sep;119(9):2550-63. doi: 10.1172/JCI33288. Epub 2009 Aug 3. J Clin Invest. 2009. PMID: 19652365 Free PMC article.

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The anti-fibrotic effect of inhibition of TGFβ-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent γ-herpesvirus infection.

Smoktunowicz N, Alexander RE, Franklin L, Williams AE, Holman B, Mercer PF, Jarai G, Scotton CJ, Chambers RC. Smoktunowicz N, et al. Among authors: scotton cj. Dis Model Mech. 2015 Sep;8(9):1129-39. doi: 10.1242/dmm.019984. Epub 2015 Jul 2. Dis Model Mech. 2015. PMID: 26138704 Free PMC article.

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Differential Expression of VEGF-A_xxx Isoforms Is Critical for Development of Pulmonary Fibrosis.

Barratt SL, Blythe T, Jarrett C, Ourradi K, Shelley-Fraser G, Day MJ, Qiu Y, Harper S, Maher TM, Oltean S, Hames TJ, Scotton CJ, Welsh GI, Bates DO, Millar AB. Barratt SL, et al. Among authors: scotton cj. Am J Respir Crit Care Med. 2017 Aug 15;196(4):479-493. doi: 10.1164/rccm.201603-0568OC. Am J Respir Crit Care Med. 2017. PMID: 28661183 Free PMC article.

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Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways.

Deng X, Mercer PF, Scotton CJ, Gilchrist A, Chambers RC. Deng X, et al. Among authors: scotton cj. Mol Biol Cell. 2008 Jun;19(6):2520-33. doi: 10.1091/mbc.e07-07-0720. Epub 2008 Mar 19. Mol Biol Cell. 2008. PMID: 18353977 Free PMC article.

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