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In search of the tumour-suppressor functions of BRCA1 and BRCA2.
Scully R, Livingston DM. Scully R, et al. Nature. 2000 Nov 23;408(6811):429-32. doi: 10.1038/35044000. Nature. 2000. PMID: 11100717 Free PMC article.
Epistatic relationships in the BRCA1-BRCA2 pathway.
Scully R. Scully R. PLoS Genet. 2011 Jul;7(7):e1002183. doi: 10.1371/journal.pgen.1002183. Epub 2011 Jul 14. PLoS Genet. 2011. PMID: 21779182 Free PMC article. No abstract available.
BRCA1 is required for postreplication repair after UV-induced DNA damage.
Pathania S, Nguyen J, Hill SJ, Scully R, Adelmant GO, Marto JA, Feunteun J, Livingston DM. Pathania S, et al. Mol Cell. 2011 Oct 21;44(2):235-51. doi: 10.1016/j.molcel.2011.09.002. Epub 2011 Sep 29. Mol Cell. 2011. PMID: 21963239 Free PMC article.
Mechanism of tandem duplication formation in BRCA1-mutant cells.
Willis NA, Frock RL, Menghi F, Duffey EE, Panday A, Camacho V, Hasty EP, Liu ET, Alt FW, Scully R. Willis NA, et al. Nature. 2017 Nov 30;551(7682):590-595. doi: 10.1038/nature24477. Epub 2017 Nov 22. Nature. 2017. PMID: 29168504 Free PMC article.
LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.
Liu XS, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs RM, Rajendran A, Xie A, Shah JV, Davis AJ, Scully R, Lunardi A, Pandolfi PP. Liu XS, et al. Nat Commun. 2015 Oct 8;6:8325. doi: 10.1038/ncomms9325. Nat Commun. 2015. PMID: 26446488 Free PMC article.
BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks.
Willis NA, Chandramouly G, Huang B, Kwok A, Follonier C, Deng C, Scully R. Willis NA, et al. Nature. 2014 Jun 26;510(7506):556-9. doi: 10.1038/nature13295. Epub 2014 Apr 28. Nature. 2014. PMID: 24776801 Free PMC article.
Double strand break repair functions of histone H2AX.
Scully R, Xie A. Scully R, et al. Mutat Res. 2013 Oct;750(1-2):5-14. doi: 10.1016/j.mrfmmm.2013.07.007. Epub 2013 Jul 31. Mutat Res. 2013. PMID: 23916969 Free PMC article. Review.
Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells.
Hartlerode AJ, Willis NA, Rajendran A, Manis JP, Scully R. Hartlerode AJ, et al. PLoS Genet. 2016 Nov 10;12(11):e1006410. doi: 10.1371/journal.pgen.1006410. eCollection 2016 Nov. PLoS Genet. 2016. PMID: 27832076 Free PMC article.
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