Sears AE - Search Results

1

Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition.

Sander CL, Sears AE, Pinto AFM, Choi EH, Kahremany S, Gao F, Salom D, Jin H, Pardon E, Suh S, Dong Z, Steyaert J, Saghatelian A, Skowronska-Krawczyk D, Kiser PD, Palczewski K. Sander CL, et al. Among authors: sears ae. J Cell Biol. 2021 Aug 2;220(8):e202101063. doi: 10.1083/jcb.202101063. Epub 2021 Jun 16. J Cell Biol. 2021. PMID: 34132745 Free PMC article.

2

Structural basis for the acyltransferase activity of lecithin:retinol acyltransferase-like proteins.

Golczak M, Kiser PD, Sears AE, Lodowski DT, Blaner WS, Palczewski K. Golczak M, et al. Among authors: sears ae. J Biol Chem. 2012 Jul 6;287(28):23790-807. doi: 10.1074/jbc.M112.361550. Epub 2012 May 17. J Biol Chem. 2012. PMID: 22605381 Free PMC article.

3

LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3.

Golczak M, Sears AE, Kiser PD, Palczewski K. Golczak M, et al. Among authors: sears ae. Nat Chem Biol. 2015 Jan;11(1):26-32. doi: 10.1038/nchembio.1687. Epub 2014 Nov 10. Nat Chem Biol. 2015. PMID: 25383759 Free PMC article.

4

An effective thiol-reactive probe for differential scanning fluorimetry with a standard real-time polymerase chain reaction device.

Hofmann L, Gulati S, Sears A, Stewart PL, Palczewski K. Hofmann L, et al. Anal Biochem. 2016 Apr 15;499:63-65. doi: 10.1016/j.ab.2016.01.016. Epub 2016 Feb 4. Anal Biochem. 2016. PMID: 26851339 Free PMC article.

5

Lecithin:Retinol Acyltransferase: A Key Enzyme Involved in the Retinoid (visual) Cycle.

Sears AE, Palczewski K. Sears AE, et al. Biochemistry. 2016 Jun 7;55(22):3082-91. doi: 10.1021/acs.biochem.6b00319. Epub 2016 May 23. Biochemistry. 2016. PMID: 27183166 Free PMC article. Review.

6

Two-photon imaging of the mammalian retina with ultrafast pulsing laser.

Palczewska G, Stremplewski P, Suh S, Alexander N, Salom D, Dong Z, Ruminski D, Choi EH, Sears AE, Kern TS, Wojtkowski M, Palczewski K. Palczewska G, et al. Among authors: sears ae. JCI Insight. 2018 Sep 6;3(17):e121555. doi: 10.1172/jci.insight.121555. eCollection 2018 Sep 6. JCI Insight. 2018. PMID: 30185665 Free PMC article.

7

Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles.

Sun D, Schur RM, Sears AE, Gao SQ, Vaidya A, Sun W, Maeda A, Kern T, Palczewski K, Lu ZR. Sun D, et al. Among authors: sears ae. Mol Ther. 2020 Jan 8;28(1):293-303. doi: 10.1016/j.ymthe.2019.09.010. Epub 2019 Sep 12. Mol Ther. 2020. PMID: 31611143 Free PMC article.

8

Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody.

Sears AE, Albiez S, Gulati S, Wang B, Kiser P, Kovacik L, Engel A, Stahlberg H, Palczewski K. Sears AE, et al. FASEB J. 2020 Oct;34(10):13918-13934. doi: 10.1096/fj.202000796RR. Epub 2020 Aug 28. FASEB J. 2020. PMID: 32860273 Free PMC article.

9

Stable Retinoid Analogue Targeted Dual pH-Sensitive Smart Lipid ECO/pDNA Nanoparticles for Specific Gene Delivery in the Retinal Pigment Epithelium.

Sun D, Schur RM, Sears AE, Gao SQ, Sun W, Naderi A, Kern T, Palczewski K, Lu ZR. Sun D, et al. Among authors: sears ae. ACS Appl Bio Mater. 2020 May 18;3(5):3078-3086. doi: 10.1021/acsabm.0c00130. Epub 2020 Apr 3. ACS Appl Bio Mater. 2020. PMID: 34327311 Free PMC article. No abstract available.

10

Genome editing in the treatment of ocular diseases.

Choi EH, Suh S, Sears AE, Hołubowicz R, Kedhar SR, Browne AW, Palczewski K. Choi EH, et al. Among authors: sears ae. Exp Mol Med. 2023 Aug;55(8):1678-1690. doi: 10.1038/s12276-023-01057-2. Epub 2023 Aug 1. Exp Mol Med. 2023. PMID: 37524870 Free PMC article. Review.

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