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Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy.
Seay HR, Putnam AL, Cserny J, Posgai AL, Rosenau EH, Wingard JR, Girard KF, Kraus M, Lares AP, Brown HL, Brown KS, Balavage KT, Peters LD, Bushdorf AN, Atkinson MA, Bluestone JA, Haller MJ, Brusko TM. Seay HR, et al. Mol Ther Methods Clin Dev. 2016 Dec 24;4:178-191. doi: 10.1016/j.omtm.2016.12.003. eCollection 2017 Mar 17. Mol Ther Methods Clin Dev. 2016. PMID: 28345003 Free PMC article.
T Cell Receptor Profiling in Type 1 Diabetes.
Jacobsen LM, Posgai A, Seay HR, Haller MJ, Brusko TM. Jacobsen LM, et al. Among authors: seay hr. Curr Diab Rep. 2017 Oct 11;17(11):118. doi: 10.1007/s11892-017-0946-4. Curr Diab Rep. 2017. PMID: 29022222 Free PMC article. Review.
Innate inflammation drives NK cell activation to impair Treg activity.
Dean JW, Peters LD, Fuhrman CA, Seay HR, Posgai AL, Stimpson SE, Brusko MA, Perry DJ, Yeh WI, Newby BN, Haller MJ, Muir AB, Atkinson MA, Mathews CE, Brusko TM. Dean JW, et al. Among authors: seay hr. J Autoimmun. 2020 Mar;108:102417. doi: 10.1016/j.jaut.2020.102417. Epub 2020 Feb 6. J Autoimmun. 2020. PMID: 32035746 Free PMC article.
Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood.
Motwani K, Peters LD, Vliegen WH, El-Sayed AG, Seay HR, Lopez MC, Baker HV, Posgai AL, Brusko MA, Perry DJ, Bacher R, Larkin J, Haller MJ, Brusko TM. Motwani K, et al. Among authors: seay hr. Front Immunol. 2020 Apr 15;11:611. doi: 10.3389/fimmu.2020.00611. eCollection 2020. Front Immunol. 2020. PMID: 32351504 Free PMC article.
Clinical Applications of Regulatory T cells in Adoptive Cell Therapies.
Marshall GP 2nd, Cserny J, Perry DJ, Yeh WI, Seay HR, Elsayed AG, Posgai AL, Brusko TM. Marshall GP 2nd, et al. Among authors: seay hr. Cell Gene Ther Insights. 2018 Jan;4(1):405-429. doi: 10.18609/cgti.2018.042. Cell Gene Ther Insights. 2018. PMID: 34984106 Free PMC article.
Human CD4+CD25+CD226- Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4+CD25+CD127lo/- Tregs for Adoptive Cell Therapy.
Brown ME, Peters LD, Hanbali SR, Arnoletti JM, Sachs LK, Nguyen KQ, Carpenter EB, Seay HR, Fuhrman CA, Posgai AL, Shapiro MR, Brusko TM. Brown ME, et al. Among authors: seay hr. Front Immunol. 2022 May 26;13:873560. doi: 10.3389/fimmu.2022.873560. eCollection 2022. Front Immunol. 2022. PMID: 35693814 Free PMC article.
Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226.
Fuhrman CA, Yeh WI, Seay HR, Saikumar Lakshmi P, Chopra G, Zhang L, Perry DJ, McClymont SA, Yadav M, Lopez MC, Baker HV, Zhang Y, Li Y, Whitley M, von Schack D, Atkinson MA, Bluestone JA, Brusko TM. Fuhrman CA, et al. Among authors: seay hr. J Immunol. 2015 Jul 1;195(1):145-55. doi: 10.4049/jimmunol.1402381. Epub 2015 May 20. J Immunol. 2015. PMID: 25994968 Free PMC article.
Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes.
Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, Vignali M, Emerson RO, Kaddis JS, Ko D, Nakayama M, Smith MJ, Cambier JC, Pugliese A, Atkinson MA, Robins HS, Brusko TM. Seay HR, et al. JCI Insight. 2016 Dec 8;1(20):e88242. doi: 10.1172/jci.insight.88242. JCI Insight. 2016. PMID: 27942583 Free PMC article.
18 results