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Targeted inhibition of farnesyltransferase in locally advanced breast cancer: a phase I and II trial of tipifarnib plus dose-dense doxorubicin and cyclophosphamide.
Sparano JA, Moulder S, Kazi A, Vahdat L, Li T, Pellegrino C, Munster P, Malafa M, Lee D, Hoschander S, Hopkins U, Hershman D, Wright JJ, Sebti SM. Sparano JA, et al. Among authors: sebti sm. J Clin Oncol. 2006 Jul 1;24(19):3013-8. doi: 10.1200/JCO.2005.04.9114. Epub 2006 Jun 12. J Clin Oncol. 2006. PMID: 16769985 Clinical Trial.
Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS.
Cohen-Jonathan E, Muschel RJ, Gillies McKenna W, Evans SM, Cerniglia G, Mick R, Kusewitt D, Sebti SM, Hamilton AD, Oliff A, Kohl N, Gibbs JB, Bernhard EJ. Cohen-Jonathan E, et al. Among authors: sebti sm. Radiat Res. 2000 Aug;154(2):125-32. doi: 10.1667/0033-7587(2000)154[0125:fiptae];2. Radiat Res. 2000. PMID: 10931682
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