Sechi M - Search Results

1

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors.

Esposito F, Sechi M, Pala N, Sanna A, Koneru PC, Kvaratskhelia M, Naesens L, Corona A, Grandi N, di Santo R, D'Amore VM, Di Leva FS, Novellino E, Cosconati S, Tramontano E. Esposito F, et al. Among authors: sechi m. Antiviral Res. 2020 Feb;174:104671. doi: 10.1016/j.antiviral.2019.104671. Epub 2019 Dec 5. Antiviral Res. 2020. PMID: 31812637

2

Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors.

Sechi M, Angotzi G, Dallocchio R, Dessì A, Carta F, Sannia L, Mariani A, Fiori S, Sanchez T, Movsessian L, Plasencia C, Neamati N. Sechi M, et al. Antivir Chem Chemother. 2004 Mar;15(2):67-81. doi: 10.1177/095632020401500203. Antivir Chem Chemother. 2004. PMID: 15185725 Free article.

3

Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.

Sechi M, Derudas M, Dallocchio R, Dessì A, Bacchi A, Sannia L, Carta F, Palomba M, Ragab O, Chan C, Shoemaker R, Sei S, Dayam R, Neamati N. Sechi M, et al. J Med Chem. 2004 Oct 7;47(21):5298-310. doi: 10.1021/jm049944f. J Med Chem. 2004. PMID: 15456274

4

Design of novel bioisosteres of beta-diketo acid inhibitors of HIV-1 integrase.

Sechi M, Sannia L, Carta F, Palomba M, Dallocchio R, Dessì A, Derudas M, Zawahir Z, Neamati N. Sechi M, et al. Antivir Chem Chemother. 2005;16(1):41-61. doi: 10.1177/095632020501600105. Antivir Chem Chemother. 2005. PMID: 15739621 Free article.

5

Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors.

Sechi M, Azzena U, Delussu MP, Dallocchio R, Dessì A, Cosseddu A, Pala N, Neamati N. Sechi M, et al. Molecules. 2008 Oct 1;13(10):2442-61. doi: 10.3390/molecules13102442. Molecules. 2008. PMID: 18830166 Free PMC article.

6

Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors.

Sechi M, Rizzi G, Bacchi A, Carcelli M, Rogolino D, Pala N, Sanchez TW, Taheri L, Dayam R, Neamati N. Sechi M, et al. Bioorg Med Chem. 2009 Apr 1;17(7):2925-35. doi: 10.1016/j.bmc.2008.10.088. Epub 2008 Nov 6. Bioorg Med Chem. 2009. PMID: 19026554

7

Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes.

Sechi M, Carta F, Sannia L, Dallocchio R, Dessì A, Al-Safi RI, Neamati N. Sechi M, et al. Antiviral Res. 2009 Mar;81(3):267-76. doi: 10.1016/j.antiviral.2008.12.010. Epub 2009 Jan 9. Antiviral Res. 2009. PMID: 19135482

8

HIV-1 IN strand transfer chelating inhibitors: a focus on metal binding.

Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N. Bacchi A, et al. Among authors: sechi m. Mol Pharm. 2011 Apr 4;8(2):507-19. doi: 10.1021/mp100343x. Epub 2011 Mar 8. Mol Pharm. 2011. PMID: 21323359

9

Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore.

Pala N, Dallocchio R, Dessì A, Brancale A, Carta F, Ihm S, Maresca A, Sechi M, Supuran CT. Pala N, et al. Among authors: sechi m. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2515-20. doi: 10.1016/j.bmcl.2011.02.059. Epub 2011 Feb 17. Bioorg Med Chem Lett. 2011. PMID: 21420862

10

Investigating the role of metal chelation in HIV-1 integrase strand transfer inhibitors.

Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Sinisi V, Neamati N. Bacchi A, et al. Among authors: sechi m. J Med Chem. 2011 Dec 22;54(24):8407-20. doi: 10.1021/jm200851g. Epub 2011 Nov 22. J Med Chem. 2011. PMID: 22066494

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