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Prenatal stress, glucocorticoids and the programming of adult disease.

Cottrell EC, Seckl JR. Cottrell EC, et al. Among authors: seckl jr. Front Behav Neurosci. 2009 Sep 7;3:19. doi: 10.3389/neuro.08.019.2009. eCollection 2009. Front Behav Neurosci. 2009. PMID: 19826624 Free PMC article.

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Glucocorticoids, feto-placental 11 beta-hydroxysteroid dehydrogenase type 2, and the early life origins of adult disease.

Seckl JR. Seckl JR. Steroids. 1997 Jan;62(1):89-94. doi: 10.1016/s0039-128x(96)00165-1. Steroids. 1997. PMID: 9029721 Review.

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Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.

Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE. Michailidou Z, et al. Among authors: seckl jr. FASEB J. 2008 Nov;22(11):3896-907. doi: 10.1096/fj.08-111914. Epub 2008 Aug 12. FASEB J. 2008. PMID: 18697839 Free PMC article.

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Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour.

Harris AP, Holmes MC, de Kloet ER, Chapman KE, Seckl JR. Harris AP, et al. Among authors: seckl jr. Psychoneuroendocrinology. 2013 May;38(5):648-58. doi: 10.1016/j.psyneuen.2012.08.007. Epub 2012 Sep 11. Psychoneuroendocrinology. 2013. PMID: 22980941

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Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology.

O'Regan D, Kenyon CJ, Seckl JR, Holmes MC. O'Regan D, et al. Among authors: seckl jr. Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E863-70. doi: 10.1152/ajpendo.00137.2004. Epub 2004 Jul 6. Am J Physiol Endocrinol Metab. 2004. PMID: 15238353 Free article.

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Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women.

Goedecke JH, Chorell E, Livingstone DE, Stimson RH, Hayes P, Adams K, Dave JA, Victor H, Levitt NS, Kahn SE, Seckl JR, Walker BR, Olsson T. Goedecke JH, et al. Among authors: seckl jr. Int J Obes (Lond). 2015 Feb;39(2):303-11. doi: 10.1038/ijo.2014.94. Epub 2014 May 20. Int J Obes (Lond). 2015. PMID: 24854429

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Preadipocyte 11beta-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo.

De Sousa Peixoto RA, Turban S, Battle JH, Chapman KE, Seckl JR, Morton NM. De Sousa Peixoto RA, et al. Among authors: seckl jr. Endocrinology. 2008 Apr;149(4):1861-8. doi: 10.1210/en.2007-1028. Epub 2008 Jan 3. Endocrinology. 2008. PMID: 18174284

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Increased maternal BMI is associated with infant wheezing in early life: a prospective cohort study.

de Vries A, Reynolds RM, Seckl JR, van der Wal M, Bonsel GJ, Vrijkotte TG. de Vries A, et al. Among authors: seckl jr. J Dev Orig Health Dis. 2014 Oct;5(5):351-60. doi: 10.1017/S2040174414000312. Epub 2014 Jun 25. J Dev Orig Health Dis. 2014. PMID: 25081820

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Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: A key mechanism in the 'foetal origins of hyperglycaemia'?

Nyirenda MJ, Dean S, Lyons V, Chapman KE, Seckl JR. Nyirenda MJ, et al. Among authors: seckl jr. Diabetologia. 2006 Jun;49(6):1412-20. doi: 10.1007/s00125-006-0188-5. Epub 2006 Mar 29. Diabetologia. 2006. PMID: 16570165

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Symptoms of depression but not anxiety are associated with central obesity and cardiovascular disease in people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study.

Labad J, Price JF, Strachan MW, Fowkes FG, Ding J, Deary IJ, Lee AJ, Frier BM, Seckl JR, Walker BR, Reynolds RM; Edinburgh Type 2 Diabetes Study Investigators. Labad J, et al. Among authors: seckl jr. Diabetologia. 2010 Mar;53(3):467-71. doi: 10.1007/s00125-009-1628-9. Epub 2009 Dec 10. Diabetologia. 2010. PMID: 20012009 Free PMC article.

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