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Your search for Second-line anticonvulsivant for convulsive status epilepticus retrieved no results
Status epilepticus: what's new for the intensivist.
Benghanem S, Pruvost-Robieux E, Neligan A, Walker MC. Benghanem S, et al. Curr Opin Crit Care. 2024 Apr 1;30(2):131-141. doi: 10.1097/MCC.0000000000001137. Epub 2024 Feb 13. Curr Opin Crit Care. 2024. PMID: 38441162 Review.
PURPOSE OF REVIEW: Status epilepticus (SE) is a common neurologic emergency affecting about 36.1/100 000 person-years that frequently requires intensive care unit (ICU) admission. ...Although we now have a good evidence-base for the initial status epilepti
PURPOSE OF REVIEW: Status epilepticus (SE) is a common neurologic emergency affecting about 36.1/100 000 person-years that fre …
Pharmacotherapy for Pediatric Convulsive Status Epilepticus.
Singh A, Stredny CM, Loddenkemper T. Singh A, et al. CNS Drugs. 2020 Jan;34(1):47-63. doi: 10.1007/s40263-019-00690-8. CNS Drugs. 2020. PMID: 31879852 Free PMC article. Review.
Convulsive status epilepticus (CSE) is one of the most common pediatric neurological emergencies. ...Simultaneously, a practice change toward more rapid initiation of first-line benzodiazepine (BZD) treatment and faster escalation to second-l
Convulsive status epilepticus (CSE) is one of the most common pediatric neurological emergencies. ...Simultaneously, a
Status epilepticus in the ICU.
Rossetti AO, Claassen J, Gaspard N. Rossetti AO, et al. Intensive Care Med. 2024 Jan;50(1):1-16. doi: 10.1007/s00134-023-07263-w. Epub 2023 Dec 20. Intensive Care Med. 2024. PMID: 38117319 Review.
Status epilepticus (SE) is a common medical emergency associated with significant morbidity and mortality. ...If possible, management of the underlying cause of seizures is crucial particularly for patients with autoimmune encephalitis. Short-term mortality r
Status epilepticus (SE) is a common medical emergency associated with significant morbidity and mortality. ...If possible, man
Status epilepticus in adults.
Betjemann JP, Lowenstein DH. Betjemann JP, et al. Lancet Neurol. 2015 Jun;14(6):615-24. doi: 10.1016/S1474-4422(15)00042-3. Epub 2015 Apr 20. Lancet Neurol. 2015. PMID: 25908090 Review.
The definition of status epilepticus as a prolonged seizure or a series of seizures with incomplete return to baseline is under reconsideration in an effort to establish a more practical definition to guide management. ...The approach of early escalation to a …
The definition of status epilepticus as a prolonged seizure or a series of seizures with incomplete return to baseline …
Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.
Lyttle MD, Rainford NEA, Gamble C, Messahel S, Humphreys A, Hickey H, Woolfall K, Roper L, Noblet J, Lee ED, Potter S, Tate P, Iyer A, Evans V, Appleton RE; Paediatric Emergency Research in the United Kingdom & Ireland (PERUKI) collaborative. Lyttle MD, et al. Lancet. 2019 May 25;393(10186):2125-2134. doi: 10.1016/S0140-6736(19)30724-X. Epub 2019 Apr 17. Lancet. 2019. PMID: 31005385 Free PMC article. Clinical Trial.
BACKGROUND: Phenytoin is the recommended second-line intravenous anticonvulsant for treatment of paediatric convulsive status epilepticus in the UK; however, some evidence suggests that levetiracetam could be an effective and safer altern …
BACKGROUND: Phenytoin is the recommended second-line intravenous anticonvulsant for treatment of paediatric convulsi
Levetiracetam versus phenytoin for second-line treatment of convulsive status epilepticus in children (ConSEPT): an open-label, multicentre, randomised controlled trial.
Dalziel SR, Borland ML, Furyk J, Bonisch M, Neutze J, Donath S, Francis KL, Sharpe C, Harvey AS, Davidson A, Craig S, Phillips N, George S, Rao A, Cheng N, Zhang M, Kochar A, Brabyn C, Oakley E, Babl FE; PREDICT research network. Dalziel SR, et al. Lancet. 2019 May 25;393(10186):2135-2145. doi: 10.1016/S0140-6736(19)30722-6. Epub 2019 Apr 17. Lancet. 2019. PMID: 31005386 Clinical Trial.
BACKGROUND: Phenytoin is the current standard of care for second-line treatment of paediatric convulsive status epilepticus after failure of first-line benzodiazepines, but is only effective in 60% of cases and is associated with consider …
BACKGROUND: Phenytoin is the current standard of care for second-line treatment of paediatric convulsive status
Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.
McTague A, Martland T, Appleton R. McTague A, et al. Cochrane Database Syst Rev. 2018 Jan 10;1(1):CD001905. doi: 10.1002/14651858.CD001905.pub3. Cochrane Database Syst Rev. 2018. PMID: 29320603 Free PMC article. Review.
BACKGROUND: Tonic-clonic convulsions and convulsive status epilepticus (currently defined as a tonic-clonic convulsion lasting at least 30 minutes) are medical emergencies and require urgent and appropriate anticonvulsant treatment. ...SE …
BACKGROUND: Tonic-clonic convulsions and convulsive status epilepticus (currently defined as a tonic-clonic c
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.
Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R; Neurological Emergencies Treatment Trials; Pediatric Emergency Care Applied Research Network investigators. Chamberlain JM, et al. Lancet. 2020 Apr 11;395(10231):1217-1224. doi: 10.1016/S0140-6736(20)30611-5. Epub 2020 Mar 20. Lancet. 2020. PMID: 32203691 Free PMC article. Clinical Trial.
In the Established Status Epilepticus Treatment Trial (ESETT) we compared the efficacy and safety of levetiracetam, fosphenytoin, and valproate in established status epilepticus, and here we describe our results after extending enrolment in children to …
In the Established Status Epilepticus Treatment Trial (ESETT) we compared the efficacy and safety of levetiracetam, fosphenyto …
Levetiracetam as an alternative to phenytoin for second-line emergency treatment of children with convulsive status epilepticus: the EcLiPSE RCT.
Appleton RE, Rainford NE, Gamble C, Messahel S, Humphreys A, Hickey H, Woolfall K, Roper L, Noblet J, Lee E, Potter S, Tate P, Al Najjar N, Iyer A, Evans V, Lyttle MD. Appleton RE, et al. Health Technol Assess. 2020 Nov;24(58):1-96. doi: 10.3310/hta24580. Health Technol Assess. 2020. PMID: 33190679 Free PMC article. Clinical Trial.

See the NIHR Journals Library website for further project information. Most epileptic tonic-clonic seizures, also called convulsions, last for < 4 minutes and stop spontaneously. A convulsion that lasts for > 5 minutes is called convulsive sta

See the NIHR Journals Library website for further project information. Most epileptic tonic-clonic seizures, also called convulsio
258 results