Sedivy JM - Search Results

1

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).

Herbig U, Jobling WA, Chen BP, Chen DJ, Sedivy JM. Herbig U, et al. Among authors: sedivy jm. Mol Cell. 2004 May 21;14(4):501-13. doi: 10.1016/s1097-2765(04)00256-4. Mol Cell. 2004. PMID: 15149599 Free article.

2

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts.

Wei W, Herbig U, Wei S, Dutriaux A, Sedivy JM. Wei W, et al. Among authors: sedivy jm. EMBO Rep. 2003 Nov;4(11):1061-6. doi: 10.1038/sj.embor.embor7400001. Epub 2003 Oct 17. EMBO Rep. 2003. PMID: 14566323 Free PMC article.

3

Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence.

Herbig U, Wei W, Dutriaux A, Jobling WA, Sedivy JM. Herbig U, et al. Among authors: sedivy jm. Aging Cell. 2003 Dec;2(6):295-304. doi: 10.1046/j.1474-9728.2003.00067.x. Aging Cell. 2003. PMID: 14677632 Free article.

4

Regulation of growth arrest in senescence: telomere damage is not the end of the story.

Herbig U, Sedivy JM. Herbig U, et al. Among authors: sedivy jm. Mech Ageing Dev. 2006 Jan;127(1):16-24. doi: 10.1016/j.mad.2005.09.002. Epub 2005 Oct 17. Mech Ageing Dev. 2006. PMID: 16229875 Review.

5

Cellular senescence in aging primates.

Herbig U, Ferreira M, Condel L, Carey D, Sedivy JM. Herbig U, et al. Among authors: sedivy jm. Science. 2006 Mar 3;311(5765):1257. doi: 10.1126/science.1122446. Epub 2006 Feb 2. Science. 2006. PMID: 16456035

6

Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts.

Wei W, Jobling WA, Chen W, Hahn WC, Sedivy JM. Wei W, et al. Among authors: sedivy jm. Mol Cell Biol. 2003 Apr;23(8):2859-70. doi: 10.1128/MCB.23.8.2859-2870.2003. Mol Cell Biol. 2003. PMID: 12665584 Free PMC article.

7

Accumulation of senescent cells in mitotic tissue of aging primates.

Jeyapalan JC, Ferreira M, Sedivy JM, Herbig U. Jeyapalan JC, et al. Among authors: sedivy jm. Mech Ageing Dev. 2007 Jan;128(1):36-44. doi: 10.1016/j.mad.2006.11.008. Epub 2006 Nov 20. Mech Ageing Dev. 2007. PMID: 17116315 Free PMC article.

8

Involvement of the INK4a/Arf gene locus in senescence.

Collins CJ, Sedivy JM. Collins CJ, et al. Among authors: sedivy jm. Aging Cell. 2003 Jun;2(3):145-50. doi: 10.1046/j.1474-9728.2003.00048.x. Aging Cell. 2003. PMID: 12882406 Free article. Review.

9

Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a).

Guney I, Wu S, Sedivy JM. Guney I, et al. Among authors: sedivy jm. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3645-50. doi: 10.1073/pnas.0600069103. Epub 2006 Feb 28. Proc Natl Acad Sci U S A. 2006. PMID: 16537449 Free PMC article.

10

Loss of protooncogene c-Myc function impedes G1 phase progression both before and after the restriction point.

Schorl C, Sedivy JM. Schorl C, et al. Among authors: sedivy jm. Mol Biol Cell. 2003 Mar;14(3):823-35. doi: 10.1091/mbc.e02-10-0649. Mol Biol Cell. 2003. PMID: 12631706 Free PMC article.

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