Seelig A - Search Results

1

Structure-activity relationship of P-glycoprotein substrates and modifiers.

Seelig A, Landwojtowicz E. Seelig A, et al. Eur J Pharm Sci. 2000 Nov;12(1):31-40. doi: 10.1016/s0928-0987(00)00177-9. Eur J Pharm Sci. 2000. PMID: 11121731

2

Predicting Activators and Inhibitors of the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1) Based on Mechanistic Considerations.

Egido E, Müller R, Li-Blatter X, Merino G, Seelig A. Egido E, et al. Among authors: seelig a. Mol Pharm. 2015 Nov 2;12(11):4026-37. doi: 10.1021/acs.molpharmaceut.5b00463. Epub 2015 Sep 30. Mol Pharm. 2015. PMID: 26372856

3

The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle.

Zolnerciks JK, Akkaya BG, Snippe M, Chiba P, Seelig A, Linton KJ. Zolnerciks JK, et al. Among authors: seelig a. FASEB J. 2014 Oct;28(10):4335-46. doi: 10.1096/fj.13-245639. Epub 2014 Jul 11. FASEB J. 2014. PMID: 25016028

4

The brain entry of HIV-1 protease inhibitors is facilitated when used in combination.

Marzolini C, Mueller R, Li-Blatter X, Battegay M, Seelig A. Marzolini C, et al. Among authors: seelig a. Mol Pharm. 2013 Jun 3;10(6):2340-9. doi: 10.1021/mp300712a. Epub 2013 May 8. Mol Pharm. 2013. PMID: 23617680

5

The role of size and charge for blood-brain barrier permeation of drugs and fatty acids.

Seelig A. Seelig A. J Mol Neurosci. 2007 Sep;33(1):32-41. doi: 10.1007/s12031-007-0055-y. J Mol Neurosci. 2007. PMID: 17901543

6

P-glycoprotein senses its substrates and the lateral membrane packing density: consequences for the catalytic cycle.

Aänismaa P, Gatlik-Landwojtowicz E, Seelig A. Aänismaa P, et al. Among authors: seelig a. Biochemistry. 2008 Sep 23;47(38):10197-207. doi: 10.1021/bi800209h. Epub 2008 Aug 30. Biochemistry. 2008. PMID: 18759452

7

Allocrite Sensing and Binding by the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1).

Xu Y, Egido E, Li-Blatter X, Müller R, Merino G, Bernèche S, Seelig A. Xu Y, et al. Among authors: seelig a. Biochemistry. 2015 Oct 13;54(40):6195-206. doi: 10.1021/acs.biochem.5b00649. Epub 2015 Sep 29. Biochemistry. 2015. PMID: 26381710

8

Sav1866 from Staphylococcus aureus and P-glycoprotein: similarities and differences in ATPase activity assessed with detergents as allocrites.

Beck A, Aänismaa P, Li-Blatter X, Dawson R, Locher K, Seelig A. Beck A, et al. Among authors: seelig a. Biochemistry. 2013 May 14;52(19):3297-309. doi: 10.1021/bi400203d. Epub 2013 May 3. Biochemistry. 2013. PMID: 23600489

9

P-glycoprotein-ATPase modulation: the molecular mechanisms.

Li-Blatter X, Beck A, Seelig A. Li-Blatter X, et al. Among authors: seelig a. Biophys J. 2012 Mar 21;102(6):1383-93. doi: 10.1016/j.bpj.2012.02.018. Epub 2012 Mar 20. Biophys J. 2012. PMID: 22455921 Free PMC article.

10

Exploring the P-glycoprotein binding cavity with polyoxyethylene alkyl ethers.

Li-Blatter X, Seelig A. Li-Blatter X, et al. Among authors: seelig a. Biophys J. 2010 Dec 1;99(11):3589-98. doi: 10.1016/j.bpj.2010.10.033. Biophys J. 2010. PMID: 21112283 Free PMC article.

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