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An ACE2-Fc decoy produced in glycoengineered plants neutralizes ancestral and newly emerging SARS-CoV-2 variants and demonstrates therapeutic efficacy in hamsters.
Föderl-Höbenreich E, Izadi S, Hofacker L, Kienzl NF, Castilho A, Strasser R, Tarrés-Freixas F, Cantero G, Roca N, Pérez M, Lorca-Oró C, Usai C, Segalés J, Vergara-Alert J, Mach L, Zatloukal K. Föderl-Höbenreich E, et al. Sci Rep. 2025 Apr 2;15(1):11307. doi: 10.1038/s41598-025-95494-w. Sci Rep. 2025. PMID: 40175560 Free PMC article.
β-Cyclodextrins as affordable antivirals to treat coronavirus infection.
Raïch-Regué D, Tenorio R, Fernández de Castro I, Tarrés-Freixas F, Sachse M, Perez-Zsolt D, Muñoz-Basagoiti J, Fernández-Sánchez SY, Gallemí M, Ortega-González P, Fernández-Oliva A, Gabaldón JA, Nuñez-Delicado E, Casas J, Roca N, Cantero G, Pérez M, Usai C, Lorca-Oró C, Alert JV, Segalés J, Carrillo J, Blanco J, Clotet Sala B, Cerón-Carrasco JP, Izquierdo-Useros N, Risco C. Raïch-Regué D, et al. Biomed Pharmacother. 2023 Aug;164:114997. doi: 10.1016/j.biopha.2023.114997. Epub 2023 Jun 8. Biomed Pharmacother. 2023. PMID: 37311279 Free PMC article.
Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.
Ávila-Nieto C, Vergara-Alert J, Amengual-Rigo P, Ainsua-Enrich E, Brustolin M, Rodríguez de la Concepción ML, Pedreño-Lopez N, Rodon J, Urrea V, Pradenas E, Marfil S, Ballana E, Riveira-Muñoz E, Pérez M, Roca N, Tarrés-Freixas F, Carabelli J, Cantero G, Pons-Grífols A, Rovirosa C, Aguilar-Gurrieri C, Ortiz R, Barajas A, Trinité B, Lepore R, Muñoz-Basagoiti J, Perez-Zsolt D, Izquierdo-Useros N, Valencia A, Blanco J, Clotet B, Guallar V, Segalés J, Carrillo J. Ávila-Nieto C, et al. Front Immunol. 2023 Dec 4;14:1291972. doi: 10.3389/fimmu.2023.1291972. eCollection 2023. Front Immunol. 2023. PMID: 38124756 Free PMC article.
SARS-CoV-2 in Captive Nonhuman Primates, Spain, 2020-2023.
Cano-Terriza D, Beato-Benítez A, Fernández-Bastit L, Segalés J, Vergara-Alert J, Martínez-Nevado E, Carretero A, Crailsheim D, Soriano P, Planas J, Torro M, García-Bocanegra I. Cano-Terriza D, et al. Emerg Infect Dis. 2024 Jun;30(6):1253-1257. doi: 10.3201/eid3006.231247. Emerg Infect Dis. 2024. PMID: 38782139 Free PMC article.
Assessment of SARS-CoV-2 exposure in exotic pets in Spain.
Cano-Terriza D, Fernández-Bastit L, Vergara-Alert J, Váquez-Calero DB, Castro-Scholten S, Caballero-Gómez J, García-Bocanegra I, Segalés J. Cano-Terriza D, et al. Comp Immunol Microbiol Infect Dis. 2025 Jan;116:102289. doi: 10.1016/j.cimid.2024.102289. Epub 2024 Dec 6. Comp Immunol Microbiol Infect Dis. 2025. PMID: 39662139 Free article.
505 results