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102 results
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DNA sequence-enabled reassembly of the green fluorescent protein.
Stains CI, Porter JR, Ooi AT, Segal DJ, Ghosh I. Stains CI, et al. Among authors: segal dj. J Am Chem Soc. 2005 Aug 10;127(31):10782-3. doi: 10.1021/ja051969w. J Am Chem Soc. 2005. PMID: 16076155
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB. Meier JL, et al. Among authors: segal dj. J Am Chem Soc. 2012 Oct 24;134(42):17814-22. doi: 10.1021/ja308888c. Epub 2012 Oct 10. J Am Chem Soc. 2012. PMID: 23013524 Free PMC article.
Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA.
Segal DJ, Crotty JW, Bhakta MS, Barbas CF 3rd, Horton NC. Segal DJ, et al. J Mol Biol. 2006 Oct 20;363(2):405-21. doi: 10.1016/j.jmb.2006.08.016. Epub 2006 Aug 11. J Mol Biol. 2006. PMID: 16963084
Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip.
Ha DT , Ghosh S , Ahn CH , Segal DJ , Kim MS . Ha DT , et al. Among authors: segal dj. Analyst. 2018 Aug 20;143(17):4009-4016. doi: 10.1039/c8an00395e. Analyst. 2018. PMID: 30043772 Free PMC article.
A zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applications.
Kim MS, Stybayeva G, Lee JY, Revzin A, Segal DJ. Kim MS, et al. Among authors: segal dj. Nucleic Acids Res. 2011 Mar;39(5):e29. doi: 10.1093/nar/gkq1214. Epub 2010 Dec 5. Nucleic Acids Res. 2011. PMID: 21134909 Free PMC article.
Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites.
Tan W, Zhu K, Segal DJ, Barbas CF 3rd, Chow SA. Tan W, et al. Among authors: segal dj. J Virol. 2004 Feb;78(3):1301-13. doi: 10.1128/jvi.78.3.1301-1313.2004. J Virol. 2004. PMID: 14722285 Free PMC article.
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. Among authors: segal dj. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.
Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER).
Porter JR, Lockwood SH, Segal DJ, Ghosh I. Porter JR, et al. Among authors: segal dj. Methods Mol Biol. 2010;649:365-82. doi: 10.1007/978-1-60761-753-2_23. Methods Mol Biol. 2010. PMID: 20680847
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Furman JL, et al. Among authors: segal dj. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457665 Free PMC article.
Critical parameters for genome editing using zinc finger nucleases.
Camenisch TD, Brilliant MH, Segal DJ. Camenisch TD, et al. Among authors: segal dj. Mini Rev Med Chem. 2008 Jun;8(7):669-76. doi: 10.2174/138955708784567458. Mini Rev Med Chem. 2008. PMID: 18537722 Review.
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