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102 results
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Site-specific detection of DNA methylation utilizing mCpG-SEER.
Stains CI, Furman JL, Segal DJ, Ghosh I. Stains CI, et al. Among authors: segal dj. J Am Chem Soc. 2006 Aug 2;128(30):9761-5. doi: 10.1021/ja060681j. J Am Chem Soc. 2006. PMID: 16866532
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing.
Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB. Meier JL, et al. Among authors: segal dj. J Am Chem Soc. 2012 Oct 24;134(42):17814-22. doi: 10.1021/ja308888c. Epub 2012 Oct 10. J Am Chem Soc. 2012. PMID: 23013524 Free PMC article.
Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip.
Ha DT , Ghosh S , Ahn CH , Segal DJ , Kim MS . Ha DT , et al. Among authors: segal dj. Analyst. 2018 Aug 20;143(17):4009-4016. doi: 10.1039/c8an00395e. Analyst. 2018. PMID: 30043772 Free PMC article.
A zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applications.
Kim MS, Stybayeva G, Lee JY, Revzin A, Segal DJ. Kim MS, et al. Among authors: segal dj. Nucleic Acids Res. 2011 Mar;39(5):e29. doi: 10.1093/nar/gkq1214. Epub 2010 Dec 5. Nucleic Acids Res. 2011. PMID: 21134909 Free PMC article.
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins.
Segal DJ, Beerli RR, Blancafort P, Dreier B, Effertz K, Huber A, Koksch B, Lund CV, Magnenat L, Valente D, Barbas CF 3rd. Segal DJ, et al. Biochemistry. 2003 Feb 25;42(7):2137-48. doi: 10.1021/bi026806o. Biochemistry. 2003. PMID: 12590603
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. Among authors: segal dj. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.
Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER).
Porter JR, Lockwood SH, Segal DJ, Ghosh I. Porter JR, et al. Among authors: segal dj. Methods Mol Biol. 2010;649:365-82. doi: 10.1007/978-1-60761-753-2_23. Methods Mol Biol. 2010. PMID: 20680847
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Furman JL, et al. Among authors: segal dj. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457665 Free PMC article.
Critical parameters for genome editing using zinc finger nucleases.
Camenisch TD, Brilliant MH, Segal DJ. Camenisch TD, et al. Among authors: segal dj. Mini Rev Med Chem. 2008 Jun;8(7):669-76. doi: 10.2174/138955708784567458. Mini Rev Med Chem. 2008. PMID: 18537722 Review.
The protein-binding potential of C2H2 zinc finger domains.
Brayer KJ, Kulshreshtha S, Segal DJ. Brayer KJ, et al. Among authors: segal dj. Cell Biochem Biophys. 2008;51(1):9-19. doi: 10.1007/s12013-008-9007-6. Epub 2008 Feb 20. Cell Biochem Biophys. 2008. PMID: 18286240
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