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102 results
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Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER).
Porter JR, Lockwood SH, Segal DJ, Ghosh I. Porter JR, et al. Among authors: segal dj. Methods Mol Biol. 2010;649:365-82. doi: 10.1007/978-1-60761-753-2_23. Methods Mol Biol. 2010. PMID: 20680847
Purified Protein Delivery to Activate an Epigenetically Silenced Allele in Mouse Brain.
Pyles B, Bailus BJ, O'Geen H, Segal DJ. Pyles B, et al. Among authors: segal dj. Methods Mol Biol. 2018;1767:227-239. doi: 10.1007/978-1-4939-7774-1_12. Methods Mol Biol. 2018. PMID: 29524138 Free PMC article.
Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA.
Segal DJ, Crotty JW, Bhakta MS, Barbas CF 3rd, Horton NC. Segal DJ, et al. J Mol Biol. 2006 Oct 20;363(2):405-21. doi: 10.1016/j.jmb.2006.08.016. Epub 2006 Aug 11. J Mol Biol. 2006. PMID: 16963084
Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip.
Ha DT , Ghosh S , Ahn CH , Segal DJ , Kim MS . Ha DT , et al. Among authors: segal dj. Analyst. 2018 Aug 20;143(17):4009-4016. doi: 10.1039/c8an00395e. Analyst. 2018. PMID: 30043772 Free PMC article.
In Vivo Applications of Cell-Penetrating Zinc-Finger Transcription Factors.
Ren C, Adams AN, Pyles B, Bailus BJ, O'Geen H, Segal DJ. Ren C, et al. Among authors: segal dj. Methods Mol Biol. 2018;1867:239-251. doi: 10.1007/978-1-4939-8799-3_18. Methods Mol Biol. 2018. PMID: 30155828 Free PMC article.
Generation and functional analysis of zinc finger nucleases.
Cathomen T, Segal DJ, Brondani V, Müller-Lerch F. Cathomen T, et al. Among authors: segal dj. Methods Mol Biol. 2008;434:277-90. doi: 10.1007/978-1-60327-248-3_17. Methods Mol Biol. 2008. PMID: 18470651
The generation of zinc finger proteins by modular assembly.
Bhakta MS, Segal DJ. Bhakta MS, et al. Among authors: segal dj. Methods Mol Biol. 2010;649:3-30. doi: 10.1007/978-1-60761-753-2_1. Methods Mol Biol. 2010. PMID: 20680825 Free PMC article.
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins.
Segal DJ, Beerli RR, Blancafort P, Dreier B, Effertz K, Huber A, Koksch B, Lund CV, Magnenat L, Valente D, Barbas CF 3rd. Segal DJ, et al. Biochemistry. 2003 Feb 25;42(7):2137-48. doi: 10.1021/bi026806o. Biochemistry. 2003. PMID: 12590603
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. Among authors: segal dj. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Furman JL, et al. Among authors: segal dj. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457665 Free PMC article.
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