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Cross-Presentation in Mouse and Human Dendritic Cells.
Segura E, Amigorena S. Segura E, et al. Adv Immunol. 2015;127:1-31. doi: 10.1016/bs.ai.2015.03.002. Epub 2015 Apr 8. Adv Immunol. 2015. PMID: 26073982 Review.
Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes.
Théry C, Duban L, Segura E, Véron P, Lantz O, Amigorena S. Théry C, et al. Among authors: segura e. Nat Immunol. 2002 Dec;3(12):1156-62. doi: 10.1038/ni854. Epub 2002 Nov 11. Nat Immunol. 2002. PMID: 12426563
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming.
Segura E, Nicco C, Lombard B, Véron P, Raposo G, Batteux F, Amigorena S, Théry C. Segura E, et al. Blood. 2005 Jul 1;106(1):216-23. doi: 10.1182/blood-2005-01-0220. Epub 2005 Mar 24. Blood. 2005. PMID: 15790784
Accumulation of MFG-E8/lactadherin on exosomes from immature dendritic cells.
Véron P, Segura E, Sugano G, Amigorena S, Théry C. Véron P, et al. Among authors: segura e. Blood Cells Mol Dis. 2005 Sep-Oct;35(2):81-8. doi: 10.1016/j.bcmd.2005.05.001. Blood Cells Mol Dis. 2005. PMID: 15982908
Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses.
Segura E, Amigorena S, Théry C. Segura E, et al. Blood Cells Mol Dis. 2005 Sep-Oct;35(2):89-93. doi: 10.1016/j.bcmd.2005.05.003. Blood Cells Mol Dis. 2005. PMID: 15990342
Since immature and mature DCs induce different functional T cell responses (i.e., tolerance versus priming), we asked whether DC maturation also influenced the priming abilities of their exosomes. ...
Since immature and mature DCs induce different functional T cell responses (i.e., tolerance versus priming), we asked whether DC matu …
Prospects for exosomes in immunotherapy of cancer.
Mignot G, Roux S, Thery C, Ségura E, Zitvogel L. Mignot G, et al. Among authors: segura e. J Cell Mol Med. 2006 Apr-Jun;10(2):376-88. doi: 10.1111/j.1582-4934.2006.tb00406.x. J Cell Mol Med. 2006. PMID: 16796806 Free PMC article. Review.
CD8+ dendritic cells use LFA-1 to capture MHC-peptide complexes from exosomes in vivo.
Segura E, Guérin C, Hogg N, Amigorena S, Théry C. Segura E, et al. J Immunol. 2007 Aug 1;179(3):1489-96. doi: 10.4049/jimmunol.179.3.1489. J Immunol. 2007. PMID: 17641014
Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses.
Bedoui S, Prato S, Mintern J, Gebhardt T, Zhan Y, Lew AM, Heath WR, Villadangos JA, Segura E. Bedoui S, et al. Among authors: segura e. J Immunol. 2009 Apr 1;182(7):4200-7. doi: 10.4049/jimmunol.0802286. J Immunol. 2009. PMID: 19299718
Antigen presentation by dendritic cells in vivo.
Segura E, Villadangos JA. Segura E, et al. Curr Opin Immunol. 2009 Feb;21(1):105-10. doi: 10.1016/j.coi.2009.03.011. Epub 2009 Apr 1. Curr Opin Immunol. 2009. PMID: 19342210 Review.
Membrane vesicles as conveyors of immune responses.
Théry C, Ostrowski M, Segura E. Théry C, et al. Among authors: segura e. Nat Rev Immunol. 2009 Aug;9(8):581-93. doi: 10.1038/nri2567. Epub 2009 Jun 5. Nat Rev Immunol. 2009. PMID: 19498381 Review.
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