Sehat B - Search Results

1

Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.

Warsito D, Lin Y, Gnirck AC, Sehat B, Larsson O. Warsito D, et al. Among authors: sehat b. Oncotarget. 2016 Jul 5;7(27):42288-42302. doi: 10.18632/oncotarget.9785. Oncotarget. 2016. PMID: 27275536 Free PMC article.

2

Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF.

Warsito D, Sjöström S, Andersson S, Larsson O, Sehat B. Warsito D, et al. Among authors: sehat b. EMBO Rep. 2012 Mar 1;13(3):244-50. doi: 10.1038/embor.2011.251. EMBO Rep. 2012. PMID: 22261717 Free PMC article.

3

Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9.

Deng H, Lin Y, Badin M, Vasilcanu D, Strömberg T, Jernberg-Wiklund H, Sehat B, Larsson O. Deng H, et al. Among authors: sehat b. Biochem Biophys Res Commun. 2011 Jan 14;404(2):667-71. doi: 10.1016/j.bbrc.2010.12.038. Epub 2010 Dec 11. Biochem Biophys Res Commun. 2011. PMID: 21147068

4

SUMOylation mediates the nuclear translocation and signaling of the IGF-1 receptor.

Sehat B, Tofigh A, Lin Y, Trocmé E, Liljedahl U, Lagergren J, Larsson O. Sehat B, et al. Sci Signal. 2010 Feb 9;3(108):ra10. doi: 10.1126/scisignal.2000628. Sci Signal. 2010. PMID: 20145208 Free article.

5

Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor.

Andersson S, D'Arcy P, Larsson O, Sehat B. Andersson S, et al. Among authors: sehat b. Biochem Biophys Res Commun. 2009 Sep 11;387(1):36-41. doi: 10.1016/j.bbrc.2009.06.088. Epub 2009 Jun 21. Biochem Biophys Res Commun. 2009. PMID: 19545541

6

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis.

Sehat B, Andersson S, Girnita L, Larsson O. Sehat B, et al. Cancer Res. 2008 Jul 15;68(14):5669-77. doi: 10.1158/0008-5472.CAN-07-6364. Cancer Res. 2008. PMID: 18632619 Free article.

7

Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.

Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, Axelson M, Girnita L. Vasilcanu R, et al. Among authors: sehat b. Mol Pharmacol. 2008 Mar;73(3):930-9. doi: 10.1124/mol.107.040014. Epub 2007 Dec 10. Mol Pharmacol. 2008. PMID: 18070930

8

Role of ubiquitination in IGF-1 receptor signaling and degradation.

Sehat B, Andersson S, Vasilcanu R, Girnita L, Larsson O. Sehat B, et al. PLoS One. 2007 Apr 4;2(4):e340. doi: 10.1371/journal.pone.0000340. PLoS One. 2007. PMID: 17406664 Free PMC article.

9

Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression.

Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Vasilcanu D, Girnita A, Lefkowitz RJ, Larsson O. Girnita L, et al. Among authors: sehat b. J Biol Chem. 2007 Apr 13;282(15):11329-38. doi: 10.1074/jbc.M611526200. Epub 2007 Feb 15. J Biol Chem. 2007. PMID: 17303558

10

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase.

Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Girnita A, Lefkowitz RJ, Larsson O. Girnita L, et al. Among authors: sehat b. J Biol Chem. 2005 Jul 1;280(26):24412-9. doi: 10.1074/jbc.M501129200. Epub 2005 May 3. J Biol Chem. 2005. PMID: 15878855

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