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A semi-automated mass spectrometric immunoassay coupled to selected reaction monitoring (MSIA-SRM) reveals novel relationships between circulating PCSK9 and metabolic phenotypes in patient cohorts.
Gauthier MS, Pérusse JR, Awan Z, Bouchard A, Tessier S, Champagne J, Krastins B, Byram G, Chabot K, Garneau P, Rabasa-Lhoret R, Faubert D, Lopez MF, Seidah NG, Coulombe B. Gauthier MS, et al. Among authors: seidah ng. Methods. 2015 Jun 15;81:66-73. doi: 10.1016/j.ymeth.2015.03.003. Epub 2015 Mar 11. Methods. 2015. PMID: 25770357
PCSK9 as a therapeutic target of dyslipidemia.
Seidah NG. Seidah NG. Expert Opin Ther Targets. 2009 Jan;13(1):19-28. doi: 10.1517/14728220802600715. Expert Opin Ther Targets. 2009. PMID: 19063703 Review.
Intestinal and hepatic cholesterol carriers in diabetic Psammomys obesus.
Levy E, Lalonde G, Delvin E, Elchebly M, Précourt LP, Seidah NG, Spahis S, Rabasa-Lhoret R, Ziv E. Levy E, et al. Among authors: seidah ng. Endocrinology. 2010 Mar;151(3):958-70. doi: 10.1210/en.2009-0866. Epub 2010 Feb 3. Endocrinology. 2010. PMID: 20130116
In vivo evidence that furin from hepatocytes inactivates PCSK9.
Essalmani R, Susan-Resiga D, Chamberland A, Abifadel M, Creemers JW, Boileau C, Seidah NG, Prat A. Essalmani R, et al. Among authors: seidah ng. J Biol Chem. 2011 Feb 11;286(6):4257-63. doi: 10.1074/jbc.M110.192104. Epub 2010 Dec 8. J Biol Chem. 2011. PMID: 21147780 Free PMC article.
672 results