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Synthesis of Derivatives of the Antibiotic Albicidin: The N-Terminal Fragment as Key to Control Potency and Resistance Mediated by the Binding Protein AlbA.
Kulike-Koczula M, Hommernick K, Ghimire LB, Kosol S, Zborovsky L, Seidel M, Sattler N, Mainz A, Weston JB, Ghilarov D, Süssmuth RD. Kulike-Koczula M, et al. Among authors: seidel m. Chemistry. 2025 Apr 9;31(21):e202500162. doi: 10.1002/chem.202500162. Epub 2025 Mar 11. Chemistry. 2025. PMID: 40024889 Free PMC article.
Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin.
Michalczyk E, Hommernick K, Behroz I, Kulike M, Pakosz-Stępień Z, Mazurek L, Seidel M, Kunert M, Santos K, von Moeller H, Loll B, Weston JB, Mainz A, Heddle JG, Süssmuth RD, Ghilarov D. Michalczyk E, et al. Among authors: seidel m. Nat Catal. 2023;6(1):52-67. doi: 10.1038/s41929-022-00904-1. Epub 2023 Jan 23. Nat Catal. 2023. PMID: 36741192 Free PMC article.
954 results