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Radioimmunotherapy for peritoneal cancers.
Seidl C, Essler M. Seidl C, et al. Immunotherapy. 2013 Apr;5(4):395-405. doi: 10.2217/imt.13.20. Immunotherapy. 2013. PMID: 23557422 Review.
Fractionated intravesical radioimmunotherapy with (213)Bi-anti-EGFR-MAb is effective without toxic side-effects in a nude mouse model of advanced human bladder carcinoma.
Fazel J, Rötzer S, Seidl C, Feuerecker B, Autenrieth M, Weirich G, Bruchertseifer F, Morgenstern A, Senekowitsch-Schmidtke R. Fazel J, et al. Cancer Biol Ther. 2015;16(10):1526-34. doi: 10.1080/15384047.2015.1071735. Epub 2015 Jul 15. Cancer Biol Ther. 2015. PMID: 26177233 Free PMC article.
α-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma.
Teiluf K, Seidl C, Blechert B, Gaertner FC, Gilbertz KP, Fernandez V, Bassermann F, Endell J, Boxhammer R, Leclair S, Vallon M, Aichler M, Feuchtinger A, Bruchertseifer F, Morgenstern A, Essler M. Teiluf K, et al. Oncotarget. 2015 Mar 10;6(7):4692-703. doi: 10.18632/oncotarget.2986. Oncotarget. 2015. PMID: 25576914 Free PMC article.
Differential gene expression triggered by highly cytotoxic alpha-emitter-immunoconjugates in gastric cancer cells.
Seidl C, Port M, Apostolidis C, Bruchertseifer F, Schwaiger M, Senekowitsch-Schmidtke R, Abend M. Seidl C, et al. Invest New Drugs. 2010 Feb;28(1):49-60. doi: 10.1007/s10637-008-9214-4. Epub 2009 Jan 13. Invest New Drugs. 2010. PMID: 19139817
Treatment of carcinoma in situ of the urinary bladder with an alpha-emitter immunoconjugate targeting the epidermal growth factor receptor: a pilot study.
Autenrieth ME, Seidl C, Bruchertseifer F, Horn T, Kurtz F, Feuerecker B, D'Alessandria C, Pfob C, Nekolla S, Apostolidis C, Mirzadeh S, Gschwend JE, Schwaiger M, Scheidhauer K, Morgenstern A. Autenrieth ME, et al. Eur J Nucl Med Mol Imaging. 2018 Jul;45(8):1364-1371. doi: 10.1007/s00259-018-4003-6. Epub 2018 Apr 11. Eur J Nucl Med Mol Imaging. 2018. PMID: 29644393
α- Versus β-Emitting Radionuclides for Pretargeted Radioimmunotherapy of Carcinoembryonic Antigen-Expressing Human Colon Cancer Xenografts.
Heskamp S, Hernandez R, Molkenboer-Kuenen JDM, Essler M, Bruchertseifer F, Morgenstern A, Steenbergen EJ, Cai W, Seidl C, McBride WJ, Goldenberg DM, Boerman OC. Heskamp S, et al. J Nucl Med. 2017 Jun;58(6):926-933. doi: 10.2967/jnumed.116.187021. Epub 2017 Feb 23. J Nucl Med. 2017. PMID: 28232604 Free PMC article.
Radioimmunotherapy with α-particle-emitting radionuclides.
Seidl C. Seidl C. Immunotherapy. 2014;6(4):431-58. doi: 10.2217/imt.14.16. Immunotherapy. 2014. PMID: 24815783 Review.
²¹³Bi-anti-EGFR radioimmunoconjugates and X-ray irradiation trigger different cell death pathways in squamous cell carcinoma cells.
Pickhard A, Piontek G, Seidl C, Kopping S, Blechert B, Mißlbeck M, Brockhoff G, Bruchertseifer F, Morgenstern A, Essler M. Pickhard A, et al. Nucl Med Biol. 2014 Jan;41(1):68-76. doi: 10.1016/j.nucmedbio.2013.09.010. Epub 2013 Oct 9. Nucl Med Biol. 2014. PMID: 24210808
Alpha-particle emitting 213Bi-anti-EGFR immunoconjugates eradicate tumor cells independent of oxygenation.
Wulbrand C, Seidl C, Gaertner FC, Bruchertseifer F, Morgenstern A, Essler M, Senekowitsch-Schmidtke R. Wulbrand C, et al. PLoS One. 2013 May 28;8(5):e64730. doi: 10.1371/journal.pone.0064730. Print 2013. PLoS One. 2013. PMID: 23724085 Free PMC article.
Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest.
Vallon M, Seidl C, Blechert B, Li Z, Gilbertz KP, Baumgart A, Aichler M, Feuchtinger A, Gaertner FC, Bruchertseifer F, Morgenstern A, Walch AK, Senekowitsch-Schmidtke R, Essler M. Vallon M, et al. Eur J Nucl Med Mol Imaging. 2012 Dec;39(12):1886-97. doi: 10.1007/s00259-012-2203-z. Epub 2012 Aug 8. Eur J Nucl Med Mol Imaging. 2012. PMID: 22872310
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