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Histamine H1-receptors in HL-60 monocytes are coupled to Gi-proteins and pertussis toxin-insensitive G-proteins and mediate activation of Ca2+ influx without concomitant Ca2+ mobilization from intracellular stores.
Seifert R, Grünbaum L, Schultz G. Seifert R, et al. Naunyn Schmiedebergs Arch Pharmacol. 1994 Apr;349(4):355-61. doi: 10.1007/BF00170880. Naunyn Schmiedebergs Arch Pharmacol. 1994. PMID: 8058107
Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates.
Taha H, Dove S, Geduhn J, König B, Shen Y, Tang WJ, Seifert R. Taha H, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2012 Jan;385(1):57-68. doi: 10.1007/s00210-011-0688-9. Epub 2011 Sep 24. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 21947230
Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes.
Erdorf M, Seifert R. Erdorf M, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2011 Apr;383(4):357-72. doi: 10.1007/s00210-011-0600-7. Epub 2011 Jan 29. Naunyn Schmiedebergs Arch Pharmacol. 2011. PMID: 21279330
Striking differences of action of lisuride stereoisomers at histamine H1 receptors.
Pertz HH, Görnemann T, Schurad B, Seifert R, Strasser A. Pertz HH, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2006 Dec;374(3):215-22. doi: 10.1007/s00210-006-0111-0. Epub 2006 Nov 8. Naunyn Schmiedebergs Arch Pharmacol. 2006. PMID: 17106670
Xanthine nucleotide-specific G-protein alpha-subunits: a novel approach for the analysis of G-protein-mediated signal transduction.
Gille A, Seifert R. Gille A, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):141-50. doi: 10.1007/s00210-003-0844-y. Epub 2003 Dec 4. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 14654999 Review.
Functional differences between human formyl peptide receptor isoforms 26, 98, and G6.
Wenzel-Seifert K, Seifert R. Wenzel-Seifert K, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2003 May;367(5):509-15. doi: 10.1007/s00210-003-0714-7. Epub 2003 Apr 5. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12679864
Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors.
Seifert R, Wenzel-Seifert K. Seifert R, et al. Naunyn Schmiedebergs Arch Pharmacol. 2002 Nov;366(5):381-416. doi: 10.1007/s00210-002-0588-0. Epub 2002 Sep 6. Naunyn Schmiedebergs Arch Pharmacol. 2002. PMID: 12382069 Review.
High constitutive Akt2 activity in U937 promonocytes: effective reduction of Akt2 phosphorylation by the histamine H2-receptor and the β2-adrenergic receptor.
Werner K, Neumann D, Seifert R. Werner K, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2016 Jan;389(1):87-101. doi: 10.1007/s00210-015-1179-1. Epub 2015 Oct 16. Naunyn Schmiedebergs Arch Pharmacol. 2016. PMID: 26475619
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor.
Reinartz MT, Kälble S, Littmann T, Ozawa T, Dove S, Kaever V, Wainer IW, Seifert R. Reinartz MT, et al. Among authors: seifert r. Naunyn Schmiedebergs Arch Pharmacol. 2015 Jan;388(1):51-65. doi: 10.1007/s00210-014-1054-5. Epub 2014 Oct 24. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 25342094
How do basic secretagogues activate mast cells?
Seifert R. Seifert R. Naunyn Schmiedebergs Arch Pharmacol. 2015 Mar;388(3):279-81. doi: 10.1007/s00210-015-1093-6. Epub 2015 Feb 1. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 25637583 No abstract available.
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