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205 results
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Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
Ebstein F, Lange N, Urban S, Seifert U, Krüger E, Kloetzel PM. Ebstein F, et al. Among authors: seifert u. Int J Biochem Cell Biol. 2009 May;41(5):1205-15. doi: 10.1016/j.biocel.2008.10.023. Epub 2008 Nov 5. Int J Biochem Cell Biol. 2009. PMID: 19028597
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing.
Huang X, Seifert U, Salzmann U, Henklein P, Preissner R, Henke W, Sijts AJ, Kloetzel PM, Dubiel W. Huang X, et al. Among authors: seifert u. J Mol Biol. 2002 Nov 1;323(4):771-82. doi: 10.1016/s0022-2836(02)00998-1. J Mol Biol. 2002. PMID: 12419264
An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.
Seifert U, Marañón C, Shmueli A, Desoutter JF, Wesoloski L, Janek K, Henklein P, Diescher S, Andrieu M, de la Salle H, Weinschenk T, Schild H, Laderach D, Galy A, Haas G, Kloetzel PM, Reiss Y, Hosmalin A. Seifert U, et al. Nat Immunol. 2003 Apr;4(4):375-9. doi: 10.1038/ni905. Epub 2003 Feb 24. Nat Immunol. 2003. PMID: 12598896
Hepatitis C virus mutation affects proteasomal epitope processing.
Seifert U, Liermann H, Racanelli V, Halenius A, Wiese M, Wedemeyer H, Ruppert T, Rispeter K, Henklein P, Sijts A, Hengel H, Kloetzel PM, Rehermann B. Seifert U, et al. J Clin Invest. 2004 Jul;114(2):250-9. doi: 10.1172/JCI20985. J Clin Invest. 2004. PMID: 15254592 Free PMC article.
Consequences of COP9 signalosome and 26S proteasome interaction.
Huang X, Hetfeld BK, Seifert U, Kähne T, Kloetzel PM, Naumann M, Bech-Otschir D, Dubiel W. Huang X, et al. Among authors: seifert u. FEBS J. 2005 Aug;272(15):3909-17. doi: 10.1111/j.1742-4658.2005.04807.x. FEBS J. 2005. PMID: 16045761
Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.
Strehl B, Seifert U, Krüger E, Heink S, Kuckelkorn U, Kloetzel PM. Strehl B, et al. Among authors: seifert u. Immunol Rev. 2005 Oct;207:19-30. doi: 10.1111/j.0105-2896.2005.00308.x. Immunol Rev. 2005. PMID: 16181324 Review.
Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells.
Młynarczuk-Biały I, Roeckmann H, Kuckelkorn U, Schmidt B, Umbreen S, Gołab J, Ludwig A, Montag C, Wiebusch L, Hagemeier C, Schadendorf D, Kloetzel PM, Seifert U. Młynarczuk-Biały I, et al. Among authors: seifert u. Cancer Res. 2006 Aug 1;66(15):7598-605. doi: 10.1158/0008-5472.CAN-05-2614. Cancer Res. 2006. PMID: 16885359
20S proteasome-dependent generation of an IEpp89 murine cytomegalovirus-derived H-2L(d) epitope from a recombinant protein.
Voigt A, Salzmann U, Seifert U, Dathe M, Soza A, Kloetzel PM, Kuckelkorn U. Voigt A, et al. Among authors: seifert u. Biochem Biophys Res Commun. 2007 Apr 6;355(2):549-54. doi: 10.1016/j.bbrc.2007.02.006. Epub 2007 Feb 8. Biochem Biophys Res Commun. 2007. PMID: 17303071
The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation.
Textoris-Taube K, Henklein P, Pollmann S, Bergann T, Weisshoff H, Seifert U, Drung I, Mügge C, Sijts A, Kloetzel PM, Kuckelkorn U. Textoris-Taube K, et al. Among authors: seifert u. J Biol Chem. 2007 Apr 27;282(17):12749-54. doi: 10.1074/jbc.M611644200. Epub 2007 Feb 16. J Biol Chem. 2007. PMID: 17308306
Remodelling of the ubiquitin-proteasome system in response to interferons.
Seifert U, Krüger E. Seifert U, et al. Biochem Soc Trans. 2008 Oct;36(Pt 5):879-84. doi: 10.1042/BST0360879. Biochem Soc Trans. 2008. PMID: 18793155
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