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Triadimefon, a fungicidal triazole-type P450 inhibitor, induces brassinosteroid deficiency-like phenotypes in plants and binds to DWF4 protein in the brassinosteroid biosynthesis pathway.
Asami T, Mizutani M, Shimada Y, Goda H, Kitahata N, Sekimata K, Han SY, Fujioka S, Takatsuto S, Sakata K, Yoshida S. Asami T, et al. Among authors: sekimata k. Biochem J. 2003 Jan 1;369(Pt 1):71-6. doi: 10.1042/BJ20020835. Biochem J. 2003. PMID: 12350224 Free PMC article.
Design and synthesis of lignostilbene-alpha,beta-dioxygenase inhibitors.
Han Sy, Inoue H, Terada T, Kamoda S, Saburi Y, Sekimata K, Saito T, Kobayashi M, Shinozaki K, Yoshida S, Asami T. Han Sy, et al. Among authors: sekimata k. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1139-42. doi: 10.1016/s0960-894x(02)00126-9. Bioorg Med Chem Lett. 2002. PMID: 11934574
N-benzylideneaniline and N-benzylaniline are potent inhibitors of lignostilbene-alpha,beta-dioxygenase, a key enzyme in oxidative cleavage of the central double bond of lignostilbene.
Han SY, Inoue H, Terada T, Kamoda S, Saburi Y, Sekimata K, Saito T, Kobayashi M, Shinozaki K, Yoshida S, Asami T. Han SY, et al. Among authors: sekimata k. J Enzyme Inhib Med Chem. 2003 Jun;18(3):279-83. doi: 10.1080/1475636031000080207. J Enzyme Inhib Med Chem. 2003. PMID: 14506920
Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva.
Yamamoto H, Sakai N, Ohte S, Sato T, Sekimata K, Matsumoto T, Nakamura K, Watanabe H, Mishima-Tsumagari C, Tanaka A, Hashizume Y, Honma T, Katagiri T, Miyazono K, Tomoda H, Shirouzu M, Koyama H. Yamamoto H, et al. Among authors: sekimata k. Bioorg Med Chem Lett. 2021 Apr 15;38:127858. doi: 10.1016/j.bmcl.2021.127858. Epub 2021 Feb 18. Bioorg Med Chem Lett. 2021. PMID: 33609658
17 results