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Selective packaging of the influenza A genome and consequences for genetic reassortment.
Gerber M, Isel C, Moules V, Marquet R. Gerber M, et al. Trends Microbiol. 2014 Aug;22(8):446-55. doi: 10.1016/j.tim.2014.04.001. Epub 2014 May 2. Trends Microbiol. 2014. PMID: 24798745 Review.
Influenza A viruses package their segmented RNA genome in a selective manner. Electron tomography, biochemical assays, and replication assays of viruses produced by reverse genetics recently unveiled molecular details of this mechanism, whereby …
Influenza A viruses package their segmented RNA genome in a selective manner. Electron tomography, biochemical a …
Organization of the Influenza A Virus Genomic RNA in the Viral Replication Cycle-Structure, Interactions, and Implications for the Emergence of New Strains.
Piasecka J, Jarmolowicz A, Kierzek E. Piasecka J, et al. Pathogens. 2020 Nov 15;9(11):951. doi: 10.3390/pathogens9110951. Pathogens. 2020. PMID: 33203084 Free PMC article. Review.
The influenza A virus is a human pathogen causing respiratory infections. The ability of this virus to trigger seasonal epidemics and sporadic pandemics is a result of its high genetic variability, leading to the ineffectiveness of vaccinations and current th …
The influenza A virus is a human pathogen causing respiratory infections. The ability of this virus to trigger seasonal epidem …
High-throughput single-virion DNA-PAINT reveals structural diversity, cooperativity, and flexibility during selective packaging in influenza.
Hepp C, Zhao Q, Robb N, Fodor E, Kapanidis AN. Hepp C, et al. Nucleic Acids Res. 2025 Oct 14;53(19):gkaf1020. doi: 10.1093/nar/gkaf1020. Nucleic Acids Res. 2025. PMID: 41099695 Free PMC article.
Influenza co-infections can result in reassortant viruses that contain gene segments from multiple strains, causing pandemic outbreaks with severe consequences for human health. The outcome of reassortment is likely influenced by a selective …
Influenza co-infections can result in reassortant viruses that contain gene segments from multiple strains, causing pandemic o …