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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1983 2
1984 2
1985 1
1986 5
1987 1
1988 3
1989 4
1990 10
1991 7
1992 14
1993 17
1994 25
1995 18
1996 38
1997 22
1998 48
1999 38
2000 44
2001 44
2002 35
2003 47
2004 56
2005 51
2006 57
2007 45
2008 56
2009 45
2010 66
2011 43
2012 46
2013 62
2014 52
2015 42
2016 50
2017 31
2018 33
2019 18
2020 25
2021 27
2022 28
2023 20
2024 1

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1,186 results

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Page 1
Psychopharmacological Treatment of Obsessive-Compulsive Disorder (OCD).
Del Casale A, Sorice S, Padovano A, Simmaco M, Ferracuti S, Lamis DA, Rapinesi C, Sani G, Girardi P, Kotzalidis GD, Pompili M. Del Casale A, et al. Curr Neuropharmacol. 2019;17(8):710-736. doi: 10.2174/1570159X16666180813155017. Curr Neuropharmacol. 2019. PMID: 30101713 Free PMC article. Review.
METHODS: We searched the PubMed database for papers dealing with drug treatment of OCD, with a specific focus on clinical guidelines, treatments with antidepressants, antipsychotics, mood stabilizers, off-label medications, and pharmacogenomics. RESULTS: Prolonged administration …
METHODS: We searched the PubMed database for papers dealing with drug treatment of OCD, with a specific focus on clinical guidelines, treatm …
Diagnosis and management of generalized anxiety disorder and panic disorder in adults.
Locke AB, Kirst N, Shultz CG. Locke AB, et al. Am Fam Physician. 2015 May 1;91(9):617-24. Am Fam Physician. 2015. PMID: 25955736 Free article. Review.
Screening and monitoring tools can be used to help make the diagnosis and monitor response to therapy. The GAD-7 and the Severity Measure for Panic Disorder are free diagnostic tools. Successful outcomes may require a combination of treatment modalities tailored to the ind …
Screening and monitoring tools can be used to help make the diagnosis and monitor response to therapy. The GAD-7 and the Severity Mea …
Pharmacotherapy for generalized anxiety disorder in adult and pediatric patients: an evidence-based treatment review.
Strawn JR, Geracioti L, Rajdev N, Clemenza K, Levine A. Strawn JR, et al. Expert Opin Pharmacother. 2018 Jul;19(10):1057-1070. doi: 10.1080/14656566.2018.1491966. Expert Opin Pharmacother. 2018. PMID: 30056792 Free PMC article. Review.
Generalized anxiety disorder (GAD) often begins during adolescence or early adulthood and persists throughout the lifespan. Randomized controlled trials support the efficacy of selective serotonin and selective serotonin norepinephrine reuptake …
Generalized anxiety disorder (GAD) often begins during adolescence or early adulthood and persists throughout the lifespan. Randomized contr …
Systematic Review and Meta-Analysis: Dose-Response Relationship of Selective Serotonin Reuptake Inhibitors in Major Depressive Disorder.
Jakubovski E, Varigonda AL, Freemantle N, Taylor MJ, Bloch MH. Jakubovski E, et al. Am J Psychiatry. 2016 Feb 1;173(2):174-83. doi: 10.1176/appi.ajp.2015.15030331. Epub 2015 Nov 10. Am J Psychiatry. 2016. PMID: 26552940 Free PMC article. Review.
OBJECTIVE: Previous studies suggested that the treatment response to selective serotonin reuptake inhibitors (SSRIs) in major depressive disorder follows a flat response curve within the therapeutic dose range. ...Trials were also require …
OBJECTIVE: Previous studies suggested that the treatment response to selective serotonin reuptake inhibitors …
Obsessive-Compulsive Disorders.
Mathews C. Mathews C. Continuum (Minneap Minn). 2021 Dec 1;27(6):1764-1784. doi: 10.1212/CON.0000000000001011. Continuum (Minneap Minn). 2021. PMID: 34881735 Review.
Cognitive-behavioral therapy (CBT), specifically a form of CBT that includes a type of behavioral intervention called exposure and response prevention, remains the most effective form of treatment for OCD. If CBT is not effective or not available, pharmacologic treatment w …
Cognitive-behavioral therapy (CBT), specifically a form of CBT that includes a type of behavioral intervention called exposure and respon …
Premenstrual Dysphoric Disorder.
Lanza di Scalea T, Pearlstein T. Lanza di Scalea T, et al. Med Clin North Am. 2019 Jul;103(4):613-628. doi: 10.1016/j.mcna.2019.02.007. Med Clin North Am. 2019. PMID: 31078196 Review.
Premenstrual dysphoric disorder (PMDD) comprises emotional and physical symptoms and functional impairment that lie on the severe end of the continuum of premenstrual symptoms. Women with PMDD have a differential response to normal hormonal fluctuations. This susceptibilit …
Premenstrual dysphoric disorder (PMDD) comprises emotional and physical symptoms and functional impairment that lie on the severe end of the …
Pharmacotherapeutic Strategies and New Targets in OCD.
Pittenger C. Pittenger C. Curr Top Behav Neurosci. 2021;49:331-384. doi: 10.1007/7854_2020_204. Curr Top Behav Neurosci. 2021. PMID: 33751503 Free PMC article. Review.
Effective pharmacological and psychotherapeutic treatments are well established for obsessive-compulsive disorder (OCD). Serotonin reuptake inhibitors (SRIs) are first-line treatment and are of benefit to about half of patients. ...We also review recent work …
Effective pharmacological and psychotherapeutic treatments are well established for obsessive-compulsive disorder (OCD). Serotonin …
Serotonin reuptake inhibitor antidepressants and abnormal bleeding: a review for clinicians and a reconsideration of mechanisms.
Andrade C, Sandarsh S, Chethan KB, Nagesh KS. Andrade C, et al. J Clin Psychiatry. 2010 Dec;71(12):1565-75. doi: 10.4088/JCP.09r05786blu. J Clin Psychiatry. 2010. PMID: 21190637 Review.
BACKGROUND: It is generally believed that selective serotonin reuptake inhibitor (SSRI) drugs increase the risk of abnormal bleeding and decrease the risk of ischemic heart disease events by blocking the uptake of serotonin into platelets, leadi …
BACKGROUND: It is generally believed that selective serotonin reuptake inhibitor (SSRI) drugs increase the risk …
Post-stroke depression: Mechanisms and pharmacological treatment.
Villa RF, Ferrari F, Moretti A. Villa RF, et al. Pharmacol Ther. 2018 Apr;184:131-144. doi: 10.1016/j.pharmthera.2017.11.005. Epub 2017 Nov 9. Pharmacol Ther. 2018. PMID: 29128343 Review.
Several lines of evidence point to a relationship between neuroinflammatory response to acute ischaemic stroke, stress activation of the hypothalamic-pituitary-adrenal (HPA) axis and the impairment of adaptive response (neurogenesis) within a background of altered e …
Several lines of evidence point to a relationship between neuroinflammatory response to acute ischaemic stroke, stress activation of …
Serotonin and brain function: a tale of two receptors.
Carhart-Harris RL, Nutt DJ. Carhart-Harris RL, et al. J Psychopharmacol. 2017 Sep;31(9):1091-1120. doi: 10.1177/0269881117725915. Epub 2017 Aug 31. J Psychopharmacol. 2017. PMID: 28858536 Free PMC article. Review.
Previous attempts to identify a unified theory of brain serotonin function have largely failed to achieve consensus. In this present synthesis, we integrate previous perspectives with new and older data to create a novel bipartite model centred on the view that serotoni …
Previous attempts to identify a unified theory of brain serotonin function have largely failed to achieve consensus. In this present …
1,186 results