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Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia.
Wan H, Selvaggio G, Pearlstein RA. Wan H, et al. Among authors: selvaggio g. PLoS One. 2020 Nov 4;15(11):e0234946. doi: 10.1371/journal.pone.0234946. eCollection 2020. PLoS One. 2020. PMID: 33147278 Free PMC article.
Evolving concepts in the pathophysiology of atherosclerosis: from endothelial dysfunction to thrombus formation through multiple shades of inflammation.
Cimmino G, Muscoli S, De Rosa S, Cesaro A, Perrone MA, Selvaggio S, Selvaggio G, Aimo A, Pedrinelli R, Mercuro G, Romeo F, Perrone Filardi P, Indolfi C, Coronelli M; Pathogenesis Of Atherosclerosis Working Group Of The Italian Society Of Cardiology. Cimmino G, et al. Among authors: selvaggio g. J Cardiovasc Med (Hagerstown). 2023 May 1;24(Suppl 2):e156-e167. doi: 10.2459/JCM.0000000000001450. J Cardiovasc Med (Hagerstown). 2023. PMID: 37186566
74 results