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Activation of PAK by a bacterial type III effector EspG reveals alternative mechanisms of GTPase pathway regulation.
Selyunin AS, Alto NM. Selyunin AS, et al. Small GTPases. 2011 Jul;2(4):217-221. doi: 10.4161/sgtp.2.4.16704. Epub 2011 Jul 1. Small GTPases. 2011. PMID: 22145094 Free PMC article.
The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.
Selyunin AS, Sutton SE, Weigele BA, Reddick LE, Orchard RC, Bresson SM, Tomchick DR, Alto NM. Selyunin AS, et al. Nature. 2011 Jan 6;469(7328):107-11. doi: 10.1038/nature09593. Epub 2010 Dec 19. Nature. 2011. PMID: 21170023 Free PMC article.
Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ.
Burnaevskiy N, Fox TG, Plymire DA, Ertelt JM, Weigele BA, Selyunin AS, Way SS, Patrie SM, Alto NM. Burnaevskiy N, et al. Among authors: selyunin as. Nature. 2013 Apr 4;496(7443):106-9. doi: 10.1038/nature12004. Epub 2013 Mar 27. Nature. 2013. PMID: 23535599 Free PMC article.
Selective protection of an ARF1-GTP signaling axis by a bacterial scaffold induces bidirectional trafficking arrest.
Selyunin AS, Reddick LE, Weigele BA, Alto NM. Selyunin AS, et al. Cell Rep. 2014 Mar 13;6(5):878-91. doi: 10.1016/j.celrep.2014.01.040. Epub 2014 Feb 27. Cell Rep. 2014. PMID: 24582959 Free PMC article.
A Conserved Structural Motif Mediates Retrograde Trafficking of Shiga Toxin Types 1 and 2.
Selyunin AS, Mukhopadhyay S. Selyunin AS, et al. Traffic. 2015 Dec;16(12):1270-87. doi: 10.1111/tra.12338. Epub 2015 Nov 2. Traffic. 2015. PMID: 26420131 Free PMC article.
Genome-wide siRNA screen identifies UNC50 as a regulator of Shiga toxin 2 trafficking.
Selyunin AS, Iles LR, Bartholomeusz G, Mukhopadhyay S. Selyunin AS, et al. J Cell Biol. 2017 Oct 2;216(10):3249-3262. doi: 10.1083/jcb.201704015. Epub 2017 Sep 7. J Cell Biol. 2017. PMID: 28883040 Free PMC article.
Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis.
Selyunin AS, Hutchens S, McHardy SF, Mukhopadhyay S. Selyunin AS, et al. Life Sci Alliance. 2019 Jun 26;2(3):e201900439. doi: 10.26508/lsa.201900439. Print 2019 Jun. Life Sci Alliance. 2019. PMID: 31243048 Free PMC article.
Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy.
Li D, Selyunin A, Mukhopadhyay S. Li D, et al. Toxins (Basel). 2020 May 22;12(5):342. doi: 10.3390/toxins12050342. Toxins (Basel). 2020. PMID: 32456007 Free PMC article. Review.