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Hypoxia and cancer.
Semenza GL. Semenza GL. Cancer Metastasis Rev. 2007 Jun;26(2):223-4. doi: 10.1007/s10555-007-9058-y. Cancer Metastasis Rev. 2007. PMID: 17404692 No abstract available.
Signal transduction to hypoxia-inducible factor 1.
Semenza G. Semenza G. Biochem Pharmacol. 2002 Sep;64(5-6):993-8. doi: 10.1016/s0006-2952(02)01168-1. Biochem Pharmacol. 2002. PMID: 12213597 Review.
Hypoxia-inducible factor 1 and cardiovascular disease.
Semenza GL. Semenza GL. Annu Rev Physiol. 2014;76:39-56. doi: 10.1146/annurev-physiol-021113-170322. Epub 2013 Aug 21. Annu Rev Physiol. 2014. PMID: 23988176 Free PMC article. Review.
Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis.
Chaturvedi P, Gilkes DM, Wong CC; Kshitiz, Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. Chaturvedi P, et al. Among authors: semenza gl. J Clin Invest. 2013 Jan;123(1):189-205. doi: 10.1172/JCI64993. Epub 2012 Dec 17. J Clin Invest. 2013. PMID: 23318994 Free PMC article.
Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells.
Sarkar K, Rey S, Zhang X, Sebastian R, Marti GP, Fox-Talbot K, Cardona AV, Du J, Tan YS, Liu L, Lay F, Gonzalez FJ, Harmon JW, Semenza GL. Sarkar K, et al. Among authors: semenza gl. Cardiovasc Res. 2012 Jan 1;93(1):162-9. doi: 10.1093/cvr/cvr282. Epub 2011 Oct 25. Cardiovasc Res. 2012. PMID: 22028336 Free PMC article.
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment.
Chaturvedi P, Gilkes DM, Takano N, Semenza GL. Chaturvedi P, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2120-9. doi: 10.1073/pnas.1406655111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799675 Free PMC article.
Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis.
Yuan G, Peng YJ, Reddy VD, Makarenko VV, Nanduri J, Khan SA, Garcia JA, Kumar GK, Semenza GL, Prabhakar NR. Yuan G, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1788-96. doi: 10.1073/pnas.1305961110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610397 Free PMC article.
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Luo W, Chang R, Zhong J, Pandey A, Semenza GL. Luo W, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):E3367-76. doi: 10.1073/pnas.1217394109. Epub 2012 Nov 5. Proc Natl Acad Sci U S A. 2012. PMID: 23129632 Free PMC article.
Oxygen homeostasis.
Semenza GL. Semenza GL. Wiley Interdiscip Rev Syst Biol Med. 2010 May-Jun;2(3):336-361. doi: 10.1002/wsbm.69. Wiley Interdiscip Rev Syst Biol Med. 2010. PMID: 20836033 Review.
Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.
Prabhakar NR, Semenza GL. Prabhakar NR, et al. Among authors: semenza gl. Physiol Rev. 2012 Jul;92(3):967-1003. doi: 10.1152/physrev.00030.2011. Physiol Rev. 2012. PMID: 22811423 Free PMC article. Review.
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