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Metabolic regulation of hematopoietic stem cells in the hypoxic niche.
Suda T, Takubo K, Semenza GL. Suda T, et al. Cell Stem Cell. 2011 Oct 4;9(4):298-310. doi: 10.1016/j.stem.2011.09.010. Cell Stem Cell. 2011. PMID: 21982230 Review.
Differentiation stage-specific requirement in hypoxia-inducible factor-1alpha-regulated glycolytic pathway during murine B cell development in bone marrow.
Kojima H, Kobayashi A, Sakurai D, Kanno Y, Hase H, Takahashi R, Totsuka Y, Semenza GL, Sitkovsky MV, Kobata T. Kojima H, et al. J Immunol. 2010 Jan 1;184(1):154-63. doi: 10.4049/jimmunol.0800167. Epub 2009 Nov 30. J Immunol. 2010. PMID: 19949104 Free PMC article.
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.
Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, Dang CV, Pardoll DM, Pan F. Dang EV, et al. Cell. 2011 Sep 2;146(5):772-84. doi: 10.1016/j.cell.2011.07.033. Epub 2011 Aug 25. Cell. 2011. PMID: 21871655 Free PMC article.
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Luo W, Hu H, Chang R, Zhong J, Knabel M, O'Meally R, Cole RN, Pandey A, Semenza GL. Luo W, et al. Cell. 2011 May 27;145(5):732-44. doi: 10.1016/j.cell.2011.03.054. Cell. 2011. PMID: 21620138 Free PMC article.
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL. Baek JH, et al. Mol Cell. 2005 Feb 18;17(4):503-12. doi: 10.1016/j.molcel.2005.01.011. Mol Cell. 2005. PMID: 15721254
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment.
Lu H, Chen I, Shimoda LA, Park Y, Zhang C, Tran L, Zhang H, Semenza GL. Lu H, et al. Cell Rep. 2017 Feb 21;18(8):1946-1957. doi: 10.1016/j.celrep.2017.02.001. Cell Rep. 2017. PMID: 28228260
Regulation of cell proliferation by hypoxia-inducible factors.
Hubbi ME, Semenza GL. Hubbi ME, et al. Am J Physiol Cell Physiol. 2015 Dec 15;309(12):C775-82. doi: 10.1152/ajpcell.00279.2015. Epub 2015 Oct 21. Am J Physiol Cell Physiol. 2015. PMID: 26491052 Free PMC article. Review.
Serine Synthesis Helps Hypoxic Cancer Stem Cells Regulate Redox.
Samanta D, Semenza GL. Samanta D, et al. Cancer Res. 2016 Nov 15;76(22):6458-6462. doi: 10.1158/0008-5472.CAN-16-1730. Epub 2016 Nov 3. Cancer Res. 2016. PMID: 27811150
In Vitro Assays of Breast Cancer Stem Cells.
Samanta D, Semenza GL. Samanta D, et al. Methods Mol Biol. 2018;1742:237-246. doi: 10.1007/978-1-4939-7665-2_21. Methods Mol Biol. 2018. PMID: 29330805
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