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Bipolar androgen therapy sensitizes castration-resistant prostate cancer to subsequent androgen receptor ablative therapy.
Sena LA, Wang H, Lim ScM SJ, Rifkind I, Ngomba N, Isaacs JT, Luo J, Pratz C, Sinibaldi V, Carducci MA, Paller CJ, Eisenberger MA, Markowski MC, Antonarakis ES, Denmeade SR. Sena LA, et al. Eur J Cancer. 2021 Feb;144:302-309. doi: 10.1016/j.ejca.2020.11.043. Epub 2020 Dec 29. Eur J Cancer. 2021. PMID: 33383350 Free PMC article. Clinical Trial.
Targeting the spectrum of immune checkpoints in prostate cancer.
Sena LA, Denmeade SR, Antonarakis ES. Sena LA, et al. Expert Rev Clin Pharmacol. 2021 Oct;14(10):1253-1266. doi: 10.1080/17512433.2021.1949287. Epub 2021 Jul 15. Expert Rev Clin Pharmacol. 2021. PMID: 34263692 Free PMC article. Review.
There are gremlins in prostate cancer.
Sena LA, Brennen WN, Isaacs JT. Sena LA, et al. Nat Cancer. 2022 May;3(5):530-531. doi: 10.1038/s43018-022-00381-2. Nat Cancer. 2022. PMID: 35624340 Free PMC article.
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC.
Sena LA, Kumar R, Sanin DE, Thompson EA, Rosen DM, Dalrymple SL, Antony L, Yang Y, Gomes-Alexandre C, Hicks JL, Jones T, Bowers KA, Eskra JN, Meyers J, Gupta A, Skaist A, Yegnasubramanian S, Luo J, Brennen WN, Kachhap SK, Antonarakis ES, De Marzo AM, Isaacs JT, Markowski MC, Denmeade SR. Sena LA, et al. J Clin Invest. 2022 Dec 1;132(23):e162396. doi: 10.1172/JCI162396. J Clin Invest. 2022. PMID: 36194476 Free PMC article.
41 results