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Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics.
Krow GR, Shoulders MD, Edupuganti R, Gandla D, Yu F, Sonnet PE, Sender M, Choudhary A, DeBrosse C, Ross CW 3rd, Carroll P, Raines RT. Krow GR, et al. Among authors: sender m. J Org Chem. 2012 Jun 15;77(12):5331-44. doi: 10.1021/jo300700a. Epub 2012 May 25. J Org Chem. 2012. PMID: 22607128 Free PMC article.
Oligomers of a 5-carboxy-methanopyrrolidine β-amino acid. A search for order.
Krow GR, Liu N, Sender M, Lin G, Centafont R, Sonnet PE, DeBrosse C, Ross CW 3rd, Carroll PJ, Shoulders MD, Raines RT. Krow GR, et al. Among authors: sender m. Org Lett. 2010 Dec 3;12(23):5438-41. doi: 10.1021/ol1022917. Epub 2010 Nov 2. Org Lett. 2010. PMID: 21043445 Free PMC article.
Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines.
Krow GR, Edupuganti R, Gandla D, Yu F, Sender M, Sonnet PE, Zdilla MJ, DeBrosse C, Cannon KC, Ross CW 3rd, Choudhary A, Shoulders MD, Raines RT. Krow GR, et al. Among authors: sender m. J Org Chem. 2011 May 20;76(10):3626-34. doi: 10.1021/jo200117p. Epub 2011 Apr 18. J Org Chem. 2011. PMID: 21500838 Free PMC article.
The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma.
Mittal P, Wang L, Akimova T, Leach CA, Clemente JC, Sender MR, Chen Y, Turunen BJ, Hancock WW. Mittal P, et al. Among authors: sender mr. Cancers (Basel). 2020 Dec 11;12(12):3723. doi: 10.3390/cancers12123723. Cancers (Basel). 2020. PMID: 33322474 Free PMC article.
Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.
Pero JE, Matthews JM, Behm DJ, Brnardic EJ, Brooks C, Budzik BW, Costell MH, Donatelli CA, Eisennagel SH, Erhard K, Fischer MC, Holt DA, Jolivette LJ, Li H, Li P, McAtee JJ, McCleland BW, Pendrak I, Posobiec LM, Rivera KLK, Rivero RA, Roethke TJ, Sender MR, Shu A, Terrell LR, Vaidya K, Xu X, Lawhorn BG. Pero JE, et al. Among authors: sender mr. J Med Chem. 2018 Dec 27;61(24):11209-11220. doi: 10.1021/acs.jmedchem.8b01344. Epub 2018 Dec 12. J Med Chem. 2018. PMID: 30500190
31 results