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Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy.
Paraskar AS, Soni S, Chin KT, Chaudhuri P, Muto KW, Berkowitz J, Handlogten MW, Alves NJ, Bilgicer B, Dinulescu DM, Mashelkar RA, Sengupta S. Paraskar AS, et al. Among authors: sengupta s. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12435-40. doi: 10.1073/pnas.1007026107. Epub 2010 Jun 23. Proc Natl Acad Sci U S A. 2010. PMID: 20616005 Free PMC article.
Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity.
Sengupta P, Basu S, Soni S, Pandey A, Roy B, Oh MS, Chin KT, Paraskar AS, Sarangi S, Connor Y, Sabbisetti VS, Kopparam J, Kulkarni A, Muto K, Amarasiriwardena C, Jayawardene I, Lupoli N, Dinulescu DM, Bonventre JV, Mashelkar RA, Sengupta S. Sengupta P, et al. Among authors: sengupta s. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11294-9. doi: 10.1073/pnas.1203129109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733767 Free PMC article.
Supramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacy.
Kulkarni AA, Roy B, Rao PS, Wyant GA, Mahmoud A, Ramachandran M, Sengupta P, Goldman A, Kotamraju VR, Basu S, Mashelkar RA, Ruoslahti E, Dinulescu DM, Sengupta S. Kulkarni AA, et al. Among authors: sengupta p, sengupta s. Cancer Res. 2013 Dec 1;73(23):6987-97. doi: 10.1158/0008-5472.CAN-12-4477. Epub 2013 Oct 11. Cancer Res. 2013. PMID: 24121488 Free PMC article.
Reporter nanoparticle that monitors its anticancer efficacy in real time.
Kulkarni A, Rao P, Natarajan S, Goldman A, Sabbisetti VS, Khater Y, Korimerla N, Chandrasekar V, Mashelkar RA, Sengupta S. Kulkarni A, et al. Among authors: sengupta s. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2104-13. doi: 10.1073/pnas.1603455113. Epub 2016 Mar 29. Proc Natl Acad Sci U S A. 2016. PMID: 27036008 Free PMC article.
2,880 results